fhir-types 0.1.115

// @generated by fhir-codegen from hl7.fhir.r5.core 5.0.0. DO NOT EDIT.
// Change the emitter (tools/fhir-codegen) and regenerate.
// SPDX-FileCopyrightText: Cadasto B.V.
// SPDX-License-Identifier: Apache-2.0
//! Investigation to increase healthcare-related patient-independent knowledge

/// Investigation to increase healthcare-related patient-independent knowledge
///
/// A scientific study of nature that sometimes includes processes involved in
/// health and disease. For example, clinical trials are research studies that
/// involve people. These studies may be related to new ways to screen, prevent,
/// diagnose, and treat disease. They may also study certain outcomes and
/// certain groups of people by looking at data collected in the past or future.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudy {
    /// Logical id of this artifact
    ///
    /// The logical id of the resource, as used in the URL for the resource. Once
    /// assigned, this value never changes.
    pub id: Option<std::string::String>,
    /// Metadata about the resource
    ///
    /// The metadata about the resource. This is content that is maintained by the
    /// infrastructure. Changes to the content might not always be associated with
    /// version changes to the resource.
    pub meta: Option<super::meta::Meta>,
    /// A set of rules under which this content was created
    ///
    /// A reference to a set of rules that were followed when the resource was
    /// constructed, and which must be understood when processing the content.
    /// Often, this is a reference to an implementation guide that defines the
    /// special rules along with other profiles etc.
    pub implicit_rules: Option<super::primitives::Uri>,
    /// Language of the resource content
    ///
    /// The base language in which the resource is written.
    pub language: Option<super::primitives::Code>,
    /// Text summary of the resource, for human interpretation
    ///
    /// A human-readable narrative that contains a summary of the resource and can
    /// be used to represent the content of the resource to a human. The narrative
    /// need not encode all the structured data, but is required to contain
    /// sufficient detail to make it "clinically safe" for a human to just read the
    /// narrative. Resource definitions may define what content should be
    /// represented in the narrative to ensure clinical safety.
    pub text: Option<super::narrative::Narrative>,
    /// Contained, inline Resources
    ///
    /// These resources do not have an independent existence apart from the resource
    /// that contains them - they cannot be identified independently, nor can they
    /// have their own independent transaction scope. This is allowed to be a
    /// Parameters resource if and only if it is referenced by a resource that
    /// provides context/meaning.
    pub contained: Vec<super::resource::Resource>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the resource. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the resource and that modifies the understanding of the
    /// element that contains it and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer is allowed to define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Canonical identifier for this study resource
    ///
    /// Canonical identifier for this study resource, represented as a globally
    /// unique URI.
    pub url: Option<super::primitives::Uri>,
    /// Business Identifier for study
    ///
    /// Identifiers assigned to this research study by the sponsor or other systems.
    pub identifier: Vec<super::identifier::Identifier>,
    /// The business version for the study record.
    pub version: Option<super::primitives::String>,
    /// Name for this study (computer friendly).
    pub name: Option<super::primitives::String>,
    /// Human readable name of the study
    ///
    /// The human readable name of the research study.
    pub title: Option<super::primitives::String>,
    /// Additional names for the study.
    pub label: Vec<ResearchStudyLabel>,
    /// Steps followed in executing study
    ///
    /// The set of steps expected to be performed as part of the execution of the
    /// study.
    pub protocol: Vec<super::reference::Reference>,
    /// Part of larger study
    ///
    /// A larger research study of which this particular study is a component or
    /// step.
    pub part_of: Vec<super::reference::Reference>,
    /// References, URLs, and attachments
    ///
    /// Citations, references, URLs and other related documents. When using
    /// relatedArtifact to share URLs, the relatedArtifact.type will often be set to
    /// one of "documentation" or "supported-with" and the URL value will often be
    /// in relatedArtifact.document.url but another possible location is
    /// relatedArtifact.resource when it is a canonical URL.
    pub related_artifact: Vec<super::related_artifact::RelatedArtifact>,
    /// Date the resource last changed
    ///
    /// The date (and optionally time) when the ResearchStudy Resource was last
    /// significantly changed. The date must change when the business version
    /// changes and it must change if the status code changes. In addition, it
    /// should change when the substantive content of the ResearchStudy Resource
    /// changes.
    pub date: Option<super::primitives::DateTime>,
    /// draft | active | retired | unknown
    ///
    /// The publication state of the resource (not of the study).
    pub status: super::primitives::Code,
    /// treatment | prevention | diagnostic | supportive-care | screening |
    /// health-services-research | basic-science | device-feasibility
    ///
    /// The type of study based upon the intent of the study activities. A
    /// classification of the intent of the study.
    pub primary_purpose_type: Option<super::codeable_concept::CodeableConcept>,
    /// n-a | early-phase-1 | phase-1 | phase-1-phase-2 | phase-2 | phase-2-phase-3
    /// | phase-3 | phase-4
    ///
    /// The stage in the progression of a therapy from initial experimental use in
    /// humans in clinical trials to post-market evaluation.
    pub phase: Option<super::codeable_concept::CodeableConcept>,
    /// Classifications of the study design characteristics
    ///
    /// Codes categorizing the type of study such as investigational vs.
    /// observational, type of blinding, type of randomization, safety vs. efficacy,
    /// etc.
    pub study_design: Vec<super::codeable_concept::CodeableConcept>,
    /// Drugs, devices, etc. under study
    ///
    /// The medication(s), food(s), therapy(ies), device(s) or other concerns or
    /// interventions that the study is seeking to gain more information about.
    pub focus: Vec<super::codeable_reference::CodeableReference>,
    /// Condition being studied
    ///
    /// The condition that is the focus of the study. For example, In a study to
    /// examine risk factors for Lupus, might have as an inclusion criterion
    /// "healthy volunteer", but the target condition code would be a Lupus SNOMED
    /// code.
    pub condition: Vec<super::codeable_concept::CodeableConcept>,
    /// Used to search for the study
    ///
    /// Key terms to aid in searching for or filtering the study.
    pub keyword: Vec<super::codeable_concept::CodeableConcept>,
    /// Geographic area for the study
    ///
    /// A country, state or other area where the study is taking place rather than
    /// its precise geographic location or address.
    pub region: Vec<super::codeable_concept::CodeableConcept>,
    /// Brief text explaining the study
    ///
    /// A brief text for explaining the study.
    pub description_summary: Option<super::primitives::Markdown>,
    /// Detailed narrative of the study
    ///
    /// A detailed and human-readable narrative of the study. E.g., study abstract.
    pub description: Option<super::primitives::Markdown>,
    /// When the study began and ended
    ///
    /// Identifies the start date and the expected (or actual, depending on status)
    /// end date for the study.
    pub period: Option<super::period::Period>,
    /// Facility where study activities are conducted
    ///
    /// A facility in which study activities are conducted.
    pub site: Vec<super::reference::Reference>,
    /// Comments made about the study
    ///
    /// Comments made about the study by the performer, subject or other
    /// participants.
    pub note: Vec<super::annotation::Annotation>,
    /// Classification for the study
    ///
    /// Additional grouping mechanism or categorization of a research study.
    /// Example: FDA regulated device, FDA regulated drug, MPG Paragraph 23b (a
    /// German legal requirement), IRB-exempt, etc. Implementation Note: do not use
    /// the classifier element to support existing semantics that are already
    /// supported thru explicit elements in the resource.
    pub classifier: Vec<super::codeable_concept::CodeableConcept>,
    /// Sponsors, collaborators, and other parties.
    pub associated_party: Vec<ResearchStudyAssociatedParty>,
    /// Status of study with time for that status.
    pub progress_status: Vec<ResearchStudyProgressStatus>,
    /// accrual-goal-met | closed-due-to-toxicity |
    /// closed-due-to-lack-of-study-progress | temporarily-closed-per-study-design
    ///
    /// A description and/or code explaining the premature termination of the study.
    pub why_stopped: Option<super::codeable_concept::CodeableConcept>,
    /// Target or actual group of participants enrolled in study.
    pub recruitment: Option<ResearchStudyRecruitment>,
    /// Defined path through the study for a subject
    ///
    /// Describes an expected event or sequence of events for one of the subjects of
    /// a study. E.g. for a living subject: exposure to drug A, wash-out, exposure
    /// to drug B, wash-out, follow-up. E.g. for a stability study: {store sample
    /// from lot A at 25 degrees for 1 month}, {store sample from lot A at 40
    /// degrees for 1 month}.
    pub comparison_group: Vec<ResearchStudyComparisonGroup>,
    /// A goal for the study
    ///
    /// A goal that the study is aiming to achieve in terms of a scientific question
    /// to be answered by the analysis of data collected during the study.
    pub objective: Vec<ResearchStudyObjective>,
    /// A variable measured during the study
    ///
    /// An "outcome measure", "endpoint", "effect measure" or "measure of effect" is
    /// a specific measurement or observation used to quantify the effect of
    /// experimental variables on the participants in a study, or for observational
    /// studies, to describe patterns of diseases or traits or associations with
    /// exposures, risk factors or treatment.
    pub outcome_measure: Vec<ResearchStudyOutcomeMeasure>,
    /// Link to results generated during the study
    ///
    /// Link to one or more sets of results generated by the study. Could also link
    /// to a research registry holding the results such as ClinicalTrials.gov.
    pub result: Vec<super::reference::Reference>,
}

impl super::super::codec::Json for ResearchStudy {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        object.insert(
            std::string::String::from("resourceType"),
            super::super::codec::Value::String(std::string::String::from("ResearchStudy")),
        );
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if let Some(item) = &self.meta {
            object.insert(
                std::string::String::from("meta"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.implicit_rules {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("implicitRules"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_implicitRules"), e);
            }
        }
        if let Some(item) = &self.language {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("language"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_language"), e);
            }
        }
        if let Some(item) = &self.text {
            object.insert(
                std::string::String::from("text"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if !self.contained.is_empty() {
            let mut items = Vec::with_capacity(self.contained.len());
            for item in &self.contained {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("contained"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.url {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("url"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_url"), e);
            }
        }
        if !self.identifier.is_empty() {
            let mut items = Vec::with_capacity(self.identifier.len());
            for item in &self.identifier {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("identifier"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.version {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("version"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_version"), e);
            }
        }
        if let Some(item) = &self.name {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("name"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_name"), e);
            }
        }
        if let Some(item) = &self.title {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("title"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_title"), e);
            }
        }
        if !self.label.is_empty() {
            let mut items = Vec::with_capacity(self.label.len());
            for item in &self.label {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("label"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.protocol.is_empty() {
            let mut items = Vec::with_capacity(self.protocol.len());
            for item in &self.protocol {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("protocol"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.part_of.is_empty() {
            let mut items = Vec::with_capacity(self.part_of.len());
            for item in &self.part_of {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("partOf"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.related_artifact.is_empty() {
            let mut items = Vec::with_capacity(self.related_artifact.len());
            for item in &self.related_artifact {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("relatedArtifact"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.date {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("date"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_date"), e);
            }
        }
        if let Some(v) = super::super::codec::Primitive::value_json(&self.status)? {
            object.insert(std::string::String::from("status"), v);
        }
        if let Some(e) = super::super::codec::Primitive::element_json(&self.status)? {
            object.insert(std::string::String::from("_status"), e);
        }
        if let Some(item) = &self.primary_purpose_type {
            object.insert(
                std::string::String::from("primaryPurposeType"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.phase {
            object.insert(
                std::string::String::from("phase"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if !self.study_design.is_empty() {
            let mut items = Vec::with_capacity(self.study_design.len());
            for item in &self.study_design {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("studyDesign"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.focus.is_empty() {
            let mut items = Vec::with_capacity(self.focus.len());
            for item in &self.focus {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("focus"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.condition.is_empty() {
            let mut items = Vec::with_capacity(self.condition.len());
            for item in &self.condition {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("condition"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.keyword.is_empty() {
            let mut items = Vec::with_capacity(self.keyword.len());
            for item in &self.keyword {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("keyword"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.region.is_empty() {
            let mut items = Vec::with_capacity(self.region.len());
            for item in &self.region {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("region"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.description_summary {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("descriptionSummary"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_descriptionSummary"), e);
            }
        }
        if let Some(item) = &self.description {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("description"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_description"), e);
            }
        }
        if let Some(item) = &self.period {
            object.insert(
                std::string::String::from("period"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if !self.site.is_empty() {
            let mut items = Vec::with_capacity(self.site.len());
            for item in &self.site {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("site"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.note.is_empty() {
            let mut items = Vec::with_capacity(self.note.len());
            for item in &self.note {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("note"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.classifier.is_empty() {
            let mut items = Vec::with_capacity(self.classifier.len());
            for item in &self.classifier {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("classifier"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.associated_party.is_empty() {
            let mut items = Vec::with_capacity(self.associated_party.len());
            for item in &self.associated_party {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("associatedParty"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.progress_status.is_empty() {
            let mut items = Vec::with_capacity(self.progress_status.len());
            for item in &self.progress_status {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("progressStatus"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.why_stopped {
            object.insert(
                std::string::String::from("whyStopped"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.recruitment {
            object.insert(
                std::string::String::from("recruitment"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if !self.comparison_group.is_empty() {
            let mut items = Vec::with_capacity(self.comparison_group.len());
            for item in &self.comparison_group {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("comparisonGroup"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.objective.is_empty() {
            let mut items = Vec::with_capacity(self.objective.len());
            for item in &self.objective {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("objective"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.outcome_measure.is_empty() {
            let mut items = Vec::with_capacity(self.outcome_measure.len());
            for item in &self.outcome_measure {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("outcomeMeasure"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.result.is_empty() {
            let mut items = Vec::with_capacity(self.result.len());
            for item in &self.result {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("result"),
                super::super::codec::Value::Array(items),
            );
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_meta: Option<&super::super::codec::Value> = None;
        let mut raw_implicit_rules: Option<&super::super::codec::Value> = None;
        let mut raw_implicit_rules_element: Option<&super::super::codec::Value> = None;
        let mut raw_language: Option<&super::super::codec::Value> = None;
        let mut raw_language_element: Option<&super::super::codec::Value> = None;
        let mut raw_text: Option<&super::super::codec::Value> = None;
        let mut raw_contained: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_url: Option<&super::super::codec::Value> = None;
        let mut raw_url_element: Option<&super::super::codec::Value> = None;
        let mut raw_identifier: Option<&super::super::codec::Value> = None;
        let mut raw_version: Option<&super::super::codec::Value> = None;
        let mut raw_version_element: Option<&super::super::codec::Value> = None;
        let mut raw_name: Option<&super::super::codec::Value> = None;
        let mut raw_name_element: Option<&super::super::codec::Value> = None;
        let mut raw_title: Option<&super::super::codec::Value> = None;
        let mut raw_title_element: Option<&super::super::codec::Value> = None;
        let mut raw_label: Option<&super::super::codec::Value> = None;
        let mut raw_protocol: Option<&super::super::codec::Value> = None;
        let mut raw_part_of: Option<&super::super::codec::Value> = None;
        let mut raw_related_artifact: Option<&super::super::codec::Value> = None;
        let mut raw_date: Option<&super::super::codec::Value> = None;
        let mut raw_date_element: Option<&super::super::codec::Value> = None;
        let mut raw_status: Option<&super::super::codec::Value> = None;
        let mut raw_status_element: Option<&super::super::codec::Value> = None;
        let mut raw_primary_purpose_type: Option<&super::super::codec::Value> = None;
        let mut raw_phase: Option<&super::super::codec::Value> = None;
        let mut raw_study_design: Option<&super::super::codec::Value> = None;
        let mut raw_focus: Option<&super::super::codec::Value> = None;
        let mut raw_condition: Option<&super::super::codec::Value> = None;
        let mut raw_keyword: Option<&super::super::codec::Value> = None;
        let mut raw_region: Option<&super::super::codec::Value> = None;
        let mut raw_description_summary: Option<&super::super::codec::Value> = None;
        let mut raw_description_summary_element: Option<&super::super::codec::Value> = None;
        let mut raw_description: Option<&super::super::codec::Value> = None;
        let mut raw_description_element: Option<&super::super::codec::Value> = None;
        let mut raw_period: Option<&super::super::codec::Value> = None;
        let mut raw_site: Option<&super::super::codec::Value> = None;
        let mut raw_note: Option<&super::super::codec::Value> = None;
        let mut raw_classifier: Option<&super::super::codec::Value> = None;
        let mut raw_associated_party: Option<&super::super::codec::Value> = None;
        let mut raw_progress_status: Option<&super::super::codec::Value> = None;
        let mut raw_why_stopped: Option<&super::super::codec::Value> = None;
        let mut raw_recruitment: Option<&super::super::codec::Value> = None;
        let mut raw_comparison_group: Option<&super::super::codec::Value> = None;
        let mut raw_objective: Option<&super::super::codec::Value> = None;
        let mut raw_outcome_measure: Option<&super::super::codec::Value> = None;
        let mut raw_result: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "resourceType" => {
                    if value.as_str() != Some("ResearchStudy") {
                        return Err(path.error(super::super::codec::DecodeErrorKind::ResourceType));
                    }
                }
                "id" => {
                    raw_id = Some(value);
                }
                "meta" => {
                    raw_meta = Some(value);
                }
                "implicitRules" => {
                    raw_implicit_rules = Some(value);
                }
                "_implicitRules" => {
                    raw_implicit_rules_element = Some(value);
                }
                "language" => {
                    raw_language = Some(value);
                }
                "_language" => {
                    raw_language_element = Some(value);
                }
                "text" => {
                    raw_text = Some(value);
                }
                "contained" => {
                    raw_contained = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "url" => {
                    raw_url = Some(value);
                }
                "_url" => {
                    raw_url_element = Some(value);
                }
                "identifier" => {
                    raw_identifier = Some(value);
                }
                "version" => {
                    raw_version = Some(value);
                }
                "_version" => {
                    raw_version_element = Some(value);
                }
                "name" => {
                    raw_name = Some(value);
                }
                "_name" => {
                    raw_name_element = Some(value);
                }
                "title" => {
                    raw_title = Some(value);
                }
                "_title" => {
                    raw_title_element = Some(value);
                }
                "label" => {
                    raw_label = Some(value);
                }
                "protocol" => {
                    raw_protocol = Some(value);
                }
                "partOf" => {
                    raw_part_of = Some(value);
                }
                "relatedArtifact" => {
                    raw_related_artifact = Some(value);
                }
                "date" => {
                    raw_date = Some(value);
                }
                "_date" => {
                    raw_date_element = Some(value);
                }
                "status" => {
                    raw_status = Some(value);
                }
                "_status" => {
                    raw_status_element = Some(value);
                }
                "primaryPurposeType" => {
                    raw_primary_purpose_type = Some(value);
                }
                "phase" => {
                    raw_phase = Some(value);
                }
                "studyDesign" => {
                    raw_study_design = Some(value);
                }
                "focus" => {
                    raw_focus = Some(value);
                }
                "condition" => {
                    raw_condition = Some(value);
                }
                "keyword" => {
                    raw_keyword = Some(value);
                }
                "region" => {
                    raw_region = Some(value);
                }
                "descriptionSummary" => {
                    raw_description_summary = Some(value);
                }
                "_descriptionSummary" => {
                    raw_description_summary_element = Some(value);
                }
                "description" => {
                    raw_description = Some(value);
                }
                "_description" => {
                    raw_description_element = Some(value);
                }
                "period" => {
                    raw_period = Some(value);
                }
                "site" => {
                    raw_site = Some(value);
                }
                "note" => {
                    raw_note = Some(value);
                }
                "classifier" => {
                    raw_classifier = Some(value);
                }
                "associatedParty" => {
                    raw_associated_party = Some(value);
                }
                "progressStatus" => {
                    raw_progress_status = Some(value);
                }
                "whyStopped" => {
                    raw_why_stopped = Some(value);
                }
                "recruitment" => {
                    raw_recruitment = Some(value);
                }
                "comparisonGroup" => {
                    raw_comparison_group = Some(value);
                }
                "objective" => {
                    raw_objective = Some(value);
                }
                "outcomeMeasure" => {
                    raw_outcome_measure = Some(value);
                }
                "result" => {
                    raw_result = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_id(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_meta = raw_meta
            .map(|value| {
                path.with("meta", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_implicit_rules = match (raw_implicit_rules, raw_implicit_rules_element) {
            (None, None) => None,
            (value, element) => Some(path.with("implicitRules", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_language = match (raw_language, raw_language_element) {
            (None, None) => None,
            (value, element) => Some(path.with("language", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_text = raw_text
            .map(|value| {
                path.with("text", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_contained = Vec::new();
        if let Some(raw) = raw_contained {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_contained.push(path.with_index("contained", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_url = match (raw_url, raw_url_element) {
            (None, None) => None,
            (value, element) => Some(path.with("url", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let mut field_identifier = Vec::new();
        if let Some(raw) = raw_identifier {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_identifier.push(path.with_index("identifier", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let field_version = match (raw_version, raw_version_element) {
            (None, None) => None,
            (value, element) => Some(path.with("version", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_name = match (raw_name, raw_name_element) {
            (None, None) => None,
            (value, element) => Some(path.with("name", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_title = match (raw_title, raw_title_element) {
            (None, None) => None,
            (value, element) => Some(path.with("title", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let mut field_label = Vec::new();
        if let Some(raw) = raw_label {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_label.push(path.with_index("label", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_protocol = Vec::new();
        if let Some(raw) = raw_protocol {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_protocol.push(path.with_index("protocol", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_part_of = Vec::new();
        if let Some(raw) = raw_part_of {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_part_of.push(path.with_index("partOf", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_related_artifact = Vec::new();
        if let Some(raw) = raw_related_artifact {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_related_artifact.push(path.with_index("relatedArtifact", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let field_date = match (raw_date, raw_date_element) {
            (None, None) => None,
            (value, element) => Some(path.with("date", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_status = path.with("status", |path| {
            super::super::codec::Primitive::from_json_parts(raw_status, raw_status_element, path)
        })?;
        let field_primary_purpose_type = raw_primary_purpose_type
            .map(|value| {
                path.with("primaryPurposeType", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_phase = raw_phase
            .map(|value| {
                path.with("phase", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_study_design = Vec::new();
        if let Some(raw) = raw_study_design {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_study_design.push(path.with_index("studyDesign", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_focus = Vec::new();
        if let Some(raw) = raw_focus {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_focus.push(path.with_index("focus", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_condition = Vec::new();
        if let Some(raw) = raw_condition {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_condition.push(path.with_index("condition", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_keyword = Vec::new();
        if let Some(raw) = raw_keyword {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_keyword.push(path.with_index("keyword", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_region = Vec::new();
        if let Some(raw) = raw_region {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_region.push(path.with_index("region", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let field_description_summary =
            match (raw_description_summary, raw_description_summary_element) {
                (None, None) => None,
                (value, element) => Some(path.with("descriptionSummary", |path| {
                    super::super::codec::Primitive::from_json_parts(value, element, path)
                })?),
            };
        let field_description = match (raw_description, raw_description_element) {
            (None, None) => None,
            (value, element) => Some(path.with("description", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_period = raw_period
            .map(|value| {
                path.with("period", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_site = Vec::new();
        if let Some(raw) = raw_site {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_site.push(path.with_index("site", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_note = Vec::new();
        if let Some(raw) = raw_note {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_note.push(path.with_index("note", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_classifier = Vec::new();
        if let Some(raw) = raw_classifier {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_classifier.push(path.with_index("classifier", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_associated_party = Vec::new();
        if let Some(raw) = raw_associated_party {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_associated_party.push(path.with_index("associatedParty", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_progress_status = Vec::new();
        if let Some(raw) = raw_progress_status {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_progress_status.push(path.with_index("progressStatus", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let field_why_stopped = raw_why_stopped
            .map(|value| {
                path.with("whyStopped", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_recruitment = raw_recruitment
            .map(|value| {
                path.with("recruitment", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_comparison_group = Vec::new();
        if let Some(raw) = raw_comparison_group {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_comparison_group.push(path.with_index("comparisonGroup", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_objective = Vec::new();
        if let Some(raw) = raw_objective {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_objective.push(path.with_index("objective", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_outcome_measure = Vec::new();
        if let Some(raw) = raw_outcome_measure {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_outcome_measure.push(path.with_index("outcomeMeasure", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_result = Vec::new();
        if let Some(raw) = raw_result {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_result.push(path.with_index("result", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        Ok(Self {
            id: field_id,
            meta: field_meta,
            implicit_rules: field_implicit_rules,
            language: field_language,
            text: field_text,
            contained: field_contained,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            url: field_url,
            identifier: field_identifier,
            version: field_version,
            name: field_name,
            title: field_title,
            label: field_label,
            protocol: field_protocol,
            part_of: field_part_of,
            related_artifact: field_related_artifact,
            date: field_date,
            status: field_status,
            primary_purpose_type: field_primary_purpose_type,
            phase: field_phase,
            study_design: field_study_design,
            focus: field_focus,
            condition: field_condition,
            keyword: field_keyword,
            region: field_region,
            description_summary: field_description_summary,
            description: field_description,
            period: field_period,
            site: field_site,
            note: field_note,
            classifier: field_classifier,
            associated_party: field_associated_party,
            progress_status: field_progress_status,
            why_stopped: field_why_stopped,
            recruitment: field_recruitment,
            comparison_group: field_comparison_group,
            objective: field_objective,
            outcome_measure: field_outcome_measure,
            result: field_result,
        })
    }
}

impl serde::Serialize for ResearchStudy {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.date {
            super::super::codec::element_entry(&mut map, "_date", item)?;
        }
        if let Some(item) = &self.description {
            super::super::codec::element_entry(&mut map, "_description", item)?;
        }
        if let Some(item) = &self.description_summary {
            super::super::codec::element_entry(&mut map, "_descriptionSummary", item)?;
        }
        if let Some(item) = &self.implicit_rules {
            super::super::codec::element_entry(&mut map, "_implicitRules", item)?;
        }
        if let Some(item) = &self.language {
            super::super::codec::element_entry(&mut map, "_language", item)?;
        }
        if let Some(item) = &self.name {
            super::super::codec::element_entry(&mut map, "_name", item)?;
        }
        super::super::codec::element_entry(&mut map, "_status", &self.status)?;
        if let Some(item) = &self.title {
            super::super::codec::element_entry(&mut map, "_title", item)?;
        }
        if let Some(item) = &self.url {
            super::super::codec::element_entry(&mut map, "_url", item)?;
        }
        if let Some(item) = &self.version {
            super::super::codec::element_entry(&mut map, "_version", item)?;
        }
        if !self.associated_party.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "associatedParty",
                &self.associated_party,
            )?;
        }
        if !self.classifier.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "classifier", &self.classifier)?;
        }
        if !self.comparison_group.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "comparisonGroup",
                &self.comparison_group,
            )?;
        }
        if !self.condition.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "condition", &self.condition)?;
        }
        if !self.contained.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "contained", &self.contained)?;
        }
        if let Some(item) = &self.date {
            super::super::codec::value_entry(&mut map, "date", item)?;
        }
        if let Some(item) = &self.description {
            super::super::codec::value_entry(&mut map, "description", item)?;
        }
        if let Some(item) = &self.description_summary {
            super::super::codec::value_entry(&mut map, "descriptionSummary", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if !self.focus.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "focus", &self.focus)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.identifier.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "identifier", &self.identifier)?;
        }
        if let Some(item) = &self.implicit_rules {
            super::super::codec::value_entry(&mut map, "implicitRules", item)?;
        }
        if !self.keyword.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "keyword", &self.keyword)?;
        }
        if !self.label.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "label", &self.label)?;
        }
        if let Some(item) = &self.language {
            super::super::codec::value_entry(&mut map, "language", item)?;
        }
        if let Some(item) = &self.meta {
            serde::ser::SerializeMap::serialize_entry(&mut map, "meta", item)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.name {
            super::super::codec::value_entry(&mut map, "name", item)?;
        }
        if !self.note.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "note", &self.note)?;
        }
        if !self.objective.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "objective", &self.objective)?;
        }
        if !self.outcome_measure.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "outcomeMeasure",
                &self.outcome_measure,
            )?;
        }
        if !self.part_of.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "partOf", &self.part_of)?;
        }
        if let Some(item) = &self.period {
            serde::ser::SerializeMap::serialize_entry(&mut map, "period", item)?;
        }
        if let Some(item) = &self.phase {
            serde::ser::SerializeMap::serialize_entry(&mut map, "phase", item)?;
        }
        if let Some(item) = &self.primary_purpose_type {
            serde::ser::SerializeMap::serialize_entry(&mut map, "primaryPurposeType", item)?;
        }
        if !self.progress_status.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "progressStatus",
                &self.progress_status,
            )?;
        }
        if !self.protocol.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "protocol", &self.protocol)?;
        }
        if let Some(item) = &self.recruitment {
            serde::ser::SerializeMap::serialize_entry(&mut map, "recruitment", item)?;
        }
        if !self.region.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "region", &self.region)?;
        }
        if !self.related_artifact.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "relatedArtifact",
                &self.related_artifact,
            )?;
        }
        serde::ser::SerializeMap::serialize_entry(&mut map, "resourceType", "ResearchStudy")?;
        if !self.result.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "result", &self.result)?;
        }
        if !self.site.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "site", &self.site)?;
        }
        super::super::codec::value_entry(&mut map, "status", &self.status)?;
        if !self.study_design.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "studyDesign", &self.study_design)?;
        }
        if let Some(item) = &self.text {
            serde::ser::SerializeMap::serialize_entry(&mut map, "text", item)?;
        }
        if let Some(item) = &self.title {
            super::super::codec::value_entry(&mut map, "title", item)?;
        }
        if let Some(item) = &self.url {
            super::super::codec::value_entry(&mut map, "url", item)?;
        }
        if let Some(item) = &self.version {
            super::super::codec::value_entry(&mut map, "version", item)?;
        }
        if let Some(item) = &self.why_stopped {
            serde::ser::SerializeMap::serialize_entry(&mut map, "whyStopped", item)?;
        }
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudy {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudy");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// Sponsors, collaborators, and other parties.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyAssociatedParty {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Name of associated party.
    pub name: Option<super::primitives::String>,
    /// sponsor | lead-sponsor | sponsor-investigator | primary-investigator |
    /// collaborator | funding-source | general-contact | recruitment-contact |
    /// sub-investigator | study-director | study-chair
    ///
    /// Type of association.
    pub role: super::codeable_concept::CodeableConcept,
    /// When active in the role
    ///
    /// Identifies the start date and the end date of the associated party in the
    /// role.
    pub period: Vec<super::period::Period>,
    /// nih | fda | government | nonprofit | academic | industry
    ///
    /// A categorization other than role for the associated party.
    pub classifier: Vec<super::codeable_concept::CodeableConcept>,
    /// Individual or organization associated with study (use practitionerRole to
    /// specify their organisation).
    pub party: Option<super::reference::Reference>,
}

impl super::super::codec::Json for ResearchStudyAssociatedParty {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.name {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("name"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_name"), e);
            }
        }
        object.insert(
            std::string::String::from("role"),
            super::super::codec::Value::Object(super::super::codec::Json::to_json(&self.role)?),
        );
        if !self.period.is_empty() {
            let mut items = Vec::with_capacity(self.period.len());
            for item in &self.period {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("period"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.classifier.is_empty() {
            let mut items = Vec::with_capacity(self.classifier.len());
            for item in &self.classifier {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("classifier"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.party {
            object.insert(
                std::string::String::from("party"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_name: Option<&super::super::codec::Value> = None;
        let mut raw_name_element: Option<&super::super::codec::Value> = None;
        let mut raw_role: Option<&super::super::codec::Value> = None;
        let mut raw_period: Option<&super::super::codec::Value> = None;
        let mut raw_classifier: Option<&super::super::codec::Value> = None;
        let mut raw_party: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "name" => {
                    raw_name = Some(value);
                }
                "_name" => {
                    raw_name_element = Some(value);
                }
                "role" => {
                    raw_role = Some(value);
                }
                "period" => {
                    raw_period = Some(value);
                }
                "classifier" => {
                    raw_classifier = Some(value);
                }
                "party" => {
                    raw_party = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_name = match (raw_name, raw_name_element) {
            (None, None) => None,
            (value, element) => Some(path.with("name", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_role = path.with("role", |path| {
            let value = raw_role
                .ok_or_else(|| path.error(super::super::codec::DecodeErrorKind::MissingProperty))?;
            super::super::codec::Json::from_json(
                super::super::codec::expect_object(
                    super::super::codec::expect_single(value, path)?,
                    path,
                )?,
                path,
            )
        })?;
        let mut field_period = Vec::new();
        if let Some(raw) = raw_period {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_period.push(path.with_index("period", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_classifier = Vec::new();
        if let Some(raw) = raw_classifier {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_classifier.push(path.with_index("classifier", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let field_party = raw_party
            .map(|value| {
                path.with("party", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            name: field_name,
            role: field_role,
            period: field_period,
            classifier: field_classifier,
            party: field_party,
        })
    }
}

impl serde::Serialize for ResearchStudyAssociatedParty {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.name {
            super::super::codec::element_entry(&mut map, "_name", item)?;
        }
        if !self.classifier.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "classifier", &self.classifier)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.name {
            super::super::codec::value_entry(&mut map, "name", item)?;
        }
        if let Some(item) = &self.party {
            serde::ser::SerializeMap::serialize_entry(&mut map, "party", item)?;
        }
        if !self.period.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "period", &self.period)?;
        }
        serde::ser::SerializeMap::serialize_entry(&mut map, "role", &self.role)?;
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyAssociatedParty {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyAssociatedParty");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// Defined path through the study for a subject
///
/// Describes an expected event or sequence of events for one of the subjects of
/// a study. E.g. for a living subject: exposure to drug A, wash-out, exposure
/// to drug B, wash-out, follow-up. E.g. for a stability study: {store sample
/// from lot A at 25 degrees for 1 month}, {store sample from lot A at 40
/// degrees for 1 month}.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyComparisonGroup {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Allows the comparisonGroup for the study and the comparisonGroup for the
    /// subject to be linked easily.
    pub link_id: Option<super::primitives::Id>,
    /// Label for study comparisonGroup
    ///
    /// Unique, human-readable label for this comparisonGroup of the study.
    pub name: super::primitives::String,
    /// Categorization of study comparisonGroup
    ///
    /// Categorization of study comparisonGroup, e.g. experimental, active
    /// comparator, placebo comparater.
    pub r#type: Option<super::codeable_concept::CodeableConcept>,
    /// Short explanation of study path
    ///
    /// A succinct description of the path through the study that would be followed
    /// by a subject adhering to this comparisonGroup.
    pub description: Option<super::primitives::Markdown>,
    /// Interventions or exposures in this comparisonGroup or cohort.
    pub intended_exposure: Vec<super::reference::Reference>,
    /// Group of participants who were enrolled in study comparisonGroup.
    pub observed_group: Option<super::reference::Reference>,
}

impl super::super::codec::Json for ResearchStudyComparisonGroup {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.link_id {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("linkId"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_linkId"), e);
            }
        }
        if let Some(v) = super::super::codec::Primitive::value_json(&self.name)? {
            object.insert(std::string::String::from("name"), v);
        }
        if let Some(e) = super::super::codec::Primitive::element_json(&self.name)? {
            object.insert(std::string::String::from("_name"), e);
        }
        if let Some(item) = &self.r#type {
            object.insert(
                std::string::String::from("type"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.description {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("description"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_description"), e);
            }
        }
        if !self.intended_exposure.is_empty() {
            let mut items = Vec::with_capacity(self.intended_exposure.len());
            for item in &self.intended_exposure {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("intendedExposure"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.observed_group {
            object.insert(
                std::string::String::from("observedGroup"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_link_id: Option<&super::super::codec::Value> = None;
        let mut raw_link_id_element: Option<&super::super::codec::Value> = None;
        let mut raw_name: Option<&super::super::codec::Value> = None;
        let mut raw_name_element: Option<&super::super::codec::Value> = None;
        let mut raw_type: Option<&super::super::codec::Value> = None;
        let mut raw_description: Option<&super::super::codec::Value> = None;
        let mut raw_description_element: Option<&super::super::codec::Value> = None;
        let mut raw_intended_exposure: Option<&super::super::codec::Value> = None;
        let mut raw_observed_group: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "linkId" => {
                    raw_link_id = Some(value);
                }
                "_linkId" => {
                    raw_link_id_element = Some(value);
                }
                "name" => {
                    raw_name = Some(value);
                }
                "_name" => {
                    raw_name_element = Some(value);
                }
                "type" => {
                    raw_type = Some(value);
                }
                "description" => {
                    raw_description = Some(value);
                }
                "_description" => {
                    raw_description_element = Some(value);
                }
                "intendedExposure" => {
                    raw_intended_exposure = Some(value);
                }
                "observedGroup" => {
                    raw_observed_group = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_link_id = match (raw_link_id, raw_link_id_element) {
            (None, None) => None,
            (value, element) => Some(path.with("linkId", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_name = path.with("name", |path| {
            super::super::codec::Primitive::from_json_parts(raw_name, raw_name_element, path)
        })?;
        let field_type = raw_type
            .map(|value| {
                path.with("type", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_description = match (raw_description, raw_description_element) {
            (None, None) => None,
            (value, element) => Some(path.with("description", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let mut field_intended_exposure = Vec::new();
        if let Some(raw) = raw_intended_exposure {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_intended_exposure.push(path.with_index(
                    "intendedExposure",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_observed_group = raw_observed_group
            .map(|value| {
                path.with("observedGroup", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            link_id: field_link_id,
            name: field_name,
            r#type: field_type,
            description: field_description,
            intended_exposure: field_intended_exposure,
            observed_group: field_observed_group,
        })
    }
}

impl serde::Serialize for ResearchStudyComparisonGroup {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.description {
            super::super::codec::element_entry(&mut map, "_description", item)?;
        }
        if let Some(item) = &self.link_id {
            super::super::codec::element_entry(&mut map, "_linkId", item)?;
        }
        super::super::codec::element_entry(&mut map, "_name", &self.name)?;
        if let Some(item) = &self.description {
            super::super::codec::value_entry(&mut map, "description", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.intended_exposure.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "intendedExposure",
                &self.intended_exposure,
            )?;
        }
        if let Some(item) = &self.link_id {
            super::super::codec::value_entry(&mut map, "linkId", item)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        super::super::codec::value_entry(&mut map, "name", &self.name)?;
        if let Some(item) = &self.observed_group {
            serde::ser::SerializeMap::serialize_entry(&mut map, "observedGroup", item)?;
        }
        if let Some(item) = &self.r#type {
            serde::ser::SerializeMap::serialize_entry(&mut map, "type", item)?;
        }
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyComparisonGroup {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyComparisonGroup");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// Additional names for the study.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyLabel {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// primary | official | scientific | plain-language | subtitle | short-title |
    /// acronym | earlier-title | language | auto-translated | human-use |
    /// machine-use | duplicate-uid
    ///
    /// Kind of name.
    pub r#type: Option<super::codeable_concept::CodeableConcept>,
    /// The name.
    pub value: Option<super::primitives::String>,
}

impl super::super::codec::Json for ResearchStudyLabel {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.r#type {
            object.insert(
                std::string::String::from("type"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.value {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("value"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_value"), e);
            }
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_type: Option<&super::super::codec::Value> = None;
        let mut raw_value: Option<&super::super::codec::Value> = None;
        let mut raw_value_element: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "type" => {
                    raw_type = Some(value);
                }
                "value" => {
                    raw_value = Some(value);
                }
                "_value" => {
                    raw_value_element = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_type = raw_type
            .map(|value| {
                path.with("type", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_value = match (raw_value, raw_value_element) {
            (None, None) => None,
            (value, element) => Some(path.with("value", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            r#type: field_type,
            value: field_value,
        })
    }
}

impl serde::Serialize for ResearchStudyLabel {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.value {
            super::super::codec::element_entry(&mut map, "_value", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.r#type {
            serde::ser::SerializeMap::serialize_entry(&mut map, "type", item)?;
        }
        if let Some(item) = &self.value {
            super::super::codec::value_entry(&mut map, "value", item)?;
        }
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyLabel {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyLabel");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// A goal for the study
///
/// A goal that the study is aiming to achieve in terms of a scientific question
/// to be answered by the analysis of data collected during the study.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyObjective {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Label for the objective
    ///
    /// Unique, human-readable label for this objective of the study.
    pub name: Option<super::primitives::String>,
    /// primary | secondary | exploratory
    ///
    /// The kind of study objective.
    pub r#type: Option<super::codeable_concept::CodeableConcept>,
    /// Description of the objective
    ///
    /// Free text description of the objective of the study. This is what the study
    /// is trying to achieve rather than how it is going to achieve it (see
    /// ResearchStudy.description).
    pub description: Option<super::primitives::Markdown>,
}

impl super::super::codec::Json for ResearchStudyObjective {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.name {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("name"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_name"), e);
            }
        }
        if let Some(item) = &self.r#type {
            object.insert(
                std::string::String::from("type"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.description {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("description"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_description"), e);
            }
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_name: Option<&super::super::codec::Value> = None;
        let mut raw_name_element: Option<&super::super::codec::Value> = None;
        let mut raw_type: Option<&super::super::codec::Value> = None;
        let mut raw_description: Option<&super::super::codec::Value> = None;
        let mut raw_description_element: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "name" => {
                    raw_name = Some(value);
                }
                "_name" => {
                    raw_name_element = Some(value);
                }
                "type" => {
                    raw_type = Some(value);
                }
                "description" => {
                    raw_description = Some(value);
                }
                "_description" => {
                    raw_description_element = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_name = match (raw_name, raw_name_element) {
            (None, None) => None,
            (value, element) => Some(path.with("name", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_type = raw_type
            .map(|value| {
                path.with("type", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_description = match (raw_description, raw_description_element) {
            (None, None) => None,
            (value, element) => Some(path.with("description", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            name: field_name,
            r#type: field_type,
            description: field_description,
        })
    }
}

impl serde::Serialize for ResearchStudyObjective {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.description {
            super::super::codec::element_entry(&mut map, "_description", item)?;
        }
        if let Some(item) = &self.name {
            super::super::codec::element_entry(&mut map, "_name", item)?;
        }
        if let Some(item) = &self.description {
            super::super::codec::value_entry(&mut map, "description", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.name {
            super::super::codec::value_entry(&mut map, "name", item)?;
        }
        if let Some(item) = &self.r#type {
            serde::ser::SerializeMap::serialize_entry(&mut map, "type", item)?;
        }
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyObjective {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyObjective");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// A variable measured during the study
///
/// An "outcome measure", "endpoint", "effect measure" or "measure of effect" is
/// a specific measurement or observation used to quantify the effect of
/// experimental variables on the participants in a study, or for observational
/// studies, to describe patterns of diseases or traits or associations with
/// exposures, risk factors or treatment.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyOutcomeMeasure {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Label for the outcome.
    pub name: Option<super::primitives::String>,
    /// primary | secondary | exploratory
    ///
    /// The parameter or characteristic being assessed as one of the values by which
    /// the study is assessed.
    pub r#type: Vec<super::codeable_concept::CodeableConcept>,
    /// Description of the outcome.
    pub description: Option<super::primitives::Markdown>,
    /// Structured outcome definition.
    pub reference: Option<super::reference::Reference>,
}

impl super::super::codec::Json for ResearchStudyOutcomeMeasure {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.name {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("name"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_name"), e);
            }
        }
        if !self.r#type.is_empty() {
            let mut items = Vec::with_capacity(self.r#type.len());
            for item in &self.r#type {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("type"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.description {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("description"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_description"), e);
            }
        }
        if let Some(item) = &self.reference {
            object.insert(
                std::string::String::from("reference"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_name: Option<&super::super::codec::Value> = None;
        let mut raw_name_element: Option<&super::super::codec::Value> = None;
        let mut raw_type: Option<&super::super::codec::Value> = None;
        let mut raw_description: Option<&super::super::codec::Value> = None;
        let mut raw_description_element: Option<&super::super::codec::Value> = None;
        let mut raw_reference: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "name" => {
                    raw_name = Some(value);
                }
                "_name" => {
                    raw_name_element = Some(value);
                }
                "type" => {
                    raw_type = Some(value);
                }
                "description" => {
                    raw_description = Some(value);
                }
                "_description" => {
                    raw_description_element = Some(value);
                }
                "reference" => {
                    raw_reference = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_name = match (raw_name, raw_name_element) {
            (None, None) => None,
            (value, element) => Some(path.with("name", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let mut field_type = Vec::new();
        if let Some(raw) = raw_type {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_type.push(path.with_index("type", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let field_description = match (raw_description, raw_description_element) {
            (None, None) => None,
            (value, element) => Some(path.with("description", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_reference = raw_reference
            .map(|value| {
                path.with("reference", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            name: field_name,
            r#type: field_type,
            description: field_description,
            reference: field_reference,
        })
    }
}

impl serde::Serialize for ResearchStudyOutcomeMeasure {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.description {
            super::super::codec::element_entry(&mut map, "_description", item)?;
        }
        if let Some(item) = &self.name {
            super::super::codec::element_entry(&mut map, "_name", item)?;
        }
        if let Some(item) = &self.description {
            super::super::codec::value_entry(&mut map, "description", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.name {
            super::super::codec::value_entry(&mut map, "name", item)?;
        }
        if let Some(item) = &self.reference {
            serde::ser::SerializeMap::serialize_entry(&mut map, "reference", item)?;
        }
        if !self.r#type.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "type", &self.r#type)?;
        }
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyOutcomeMeasure {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyOutcomeMeasure");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// Status of study with time for that status.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyProgressStatus {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Label for status or state (e.g. recruitment status).
    pub state: super::codeable_concept::CodeableConcept,
    /// Actual if true else anticipated
    ///
    /// An indication of whether or not the date is a known date when the state
    /// changed or will change. A value of true indicates a known date. A value of
    /// false indicates an estimated date.
    pub actual: Option<super::primitives::Boolean>,
    /// Date range.
    pub period: Option<super::period::Period>,
}

impl super::super::codec::Json for ResearchStudyProgressStatus {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        object.insert(
            std::string::String::from("state"),
            super::super::codec::Value::Object(super::super::codec::Json::to_json(&self.state)?),
        );
        if let Some(item) = &self.actual {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("actual"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_actual"), e);
            }
        }
        if let Some(item) = &self.period {
            object.insert(
                std::string::String::from("period"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_state: Option<&super::super::codec::Value> = None;
        let mut raw_actual: Option<&super::super::codec::Value> = None;
        let mut raw_actual_element: Option<&super::super::codec::Value> = None;
        let mut raw_period: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "state" => {
                    raw_state = Some(value);
                }
                "actual" => {
                    raw_actual = Some(value);
                }
                "_actual" => {
                    raw_actual_element = Some(value);
                }
                "period" => {
                    raw_period = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_state = path.with("state", |path| {
            let value = raw_state
                .ok_or_else(|| path.error(super::super::codec::DecodeErrorKind::MissingProperty))?;
            super::super::codec::Json::from_json(
                super::super::codec::expect_object(
                    super::super::codec::expect_single(value, path)?,
                    path,
                )?,
                path,
            )
        })?;
        let field_actual = match (raw_actual, raw_actual_element) {
            (None, None) => None,
            (value, element) => Some(path.with("actual", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_period = raw_period
            .map(|value| {
                path.with("period", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            state: field_state,
            actual: field_actual,
            period: field_period,
        })
    }
}

impl serde::Serialize for ResearchStudyProgressStatus {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.actual {
            super::super::codec::element_entry(&mut map, "_actual", item)?;
        }
        if let Some(item) = &self.actual {
            super::super::codec::value_entry(&mut map, "actual", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.period {
            serde::ser::SerializeMap::serialize_entry(&mut map, "period", item)?;
        }
        serde::ser::SerializeMap::serialize_entry(&mut map, "state", &self.state)?;
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyProgressStatus {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyProgressStatus");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}

/// Target or actual group of participants enrolled in study.
#[derive(Debug, Clone, Default, PartialEq, Eq)]
pub struct ResearchStudyRecruitment {
    /// Unique id for inter-element referencing
    ///
    /// Unique id for the element within a resource (for internal references). This
    /// may be any string value that does not contain spaces.
    pub id: Option<std::string::String>,
    /// Additional content defined by implementations
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element. To make the use of extensions safe and
    /// managable, there is a strict set of governance applied to the definition and
    /// use of extensions. Though any implementer can define an extension, there is
    /// a set of requirements that SHALL be met as part of the definition of the
    /// extension.
    pub extension: Vec<super::extension::Extension>,
    /// Extensions that cannot be ignored even if unrecognized
    ///
    /// May be used to represent additional information that is not part of the
    /// basic definition of the element and that modifies the understanding of the
    /// element in which it is contained and/or the understanding of the containing
    /// element's descendants. Usually modifier elements provide negation or
    /// qualification. To make the use of extensions safe and managable, there is a
    /// strict set of governance applied to the definition and use of extensions.
    /// Though any implementer can define an extension, there is a set of
    /// requirements that SHALL be met as part of the definition of the extension.
    /// Applications processing a resource are required to check for modifier
    /// extensions. Modifier extensions SHALL NOT change the meaning of any elements
    /// on Resource or DomainResource (including cannot change the meaning of
    /// modifierExtension itself).
    pub modifier_extension: Vec<super::extension::Extension>,
    /// Estimated total number of participants to be enrolled.
    pub target_number: Option<super::primitives::UnsignedInt>,
    /// Actual total number of participants enrolled in study.
    pub actual_number: Option<super::primitives::UnsignedInt>,
    /// Inclusion and exclusion criteria.
    pub eligibility: Option<super::reference::Reference>,
    /// Group of participants who were enrolled in study.
    pub actual_group: Option<super::reference::Reference>,
}

impl super::super::codec::Json for ResearchStudyRecruitment {
    fn to_json(&self) -> Result<super::super::codec::Object, super::super::codec::EncodeError> {
        let mut object = super::super::codec::Object::new();
        if let Some(v) = &self.id {
            object.insert(
                std::string::String::from("id"),
                super::super::codec::Value::String(v.clone()),
            );
        }
        if !self.extension.is_empty() {
            let mut items = Vec::with_capacity(self.extension.len());
            for item in &self.extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("extension"),
                super::super::codec::Value::Array(items),
            );
        }
        if !self.modifier_extension.is_empty() {
            let mut items = Vec::with_capacity(self.modifier_extension.len());
            for item in &self.modifier_extension {
                items.push(super::super::codec::Value::Object(
                    super::super::codec::Json::to_json(item)?,
                ));
            }
            object.insert(
                std::string::String::from("modifierExtension"),
                super::super::codec::Value::Array(items),
            );
        }
        if let Some(item) = &self.target_number {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("targetNumber"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_targetNumber"), e);
            }
        }
        if let Some(item) = &self.actual_number {
            if let Some(v) = super::super::codec::Primitive::value_json(item)? {
                object.insert(std::string::String::from("actualNumber"), v);
            }
            if let Some(e) = super::super::codec::Primitive::element_json(item)? {
                object.insert(std::string::String::from("_actualNumber"), e);
            }
        }
        if let Some(item) = &self.eligibility {
            object.insert(
                std::string::String::from("eligibility"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        if let Some(item) = &self.actual_group {
            object.insert(
                std::string::String::from("actualGroup"),
                super::super::codec::Value::Object(super::super::codec::Json::to_json(item)?),
            );
        }
        Ok(object)
    }

    fn from_json(
        object: &super::super::codec::Object,
        path: &mut super::super::codec::Path,
    ) -> Result<Self, super::super::codec::DecodeError> {
        let mut raw_id: Option<&super::super::codec::Value> = None;
        let mut raw_extension: Option<&super::super::codec::Value> = None;
        let mut raw_modifier_extension: Option<&super::super::codec::Value> = None;
        let mut raw_target_number: Option<&super::super::codec::Value> = None;
        let mut raw_target_number_element: Option<&super::super::codec::Value> = None;
        let mut raw_actual_number: Option<&super::super::codec::Value> = None;
        let mut raw_actual_number_element: Option<&super::super::codec::Value> = None;
        let mut raw_eligibility: Option<&super::super::codec::Value> = None;
        let mut raw_actual_group: Option<&super::super::codec::Value> = None;
        for (key, value) in object {
            match key.as_str() {
                "id" => {
                    raw_id = Some(value);
                }
                "extension" => {
                    raw_extension = Some(value);
                }
                "modifierExtension" => {
                    raw_modifier_extension = Some(value);
                }
                "targetNumber" => {
                    raw_target_number = Some(value);
                }
                "_targetNumber" => {
                    raw_target_number_element = Some(value);
                }
                "actualNumber" => {
                    raw_actual_number = Some(value);
                }
                "_actualNumber" => {
                    raw_actual_number_element = Some(value);
                }
                "eligibility" => {
                    raw_eligibility = Some(value);
                }
                "actualGroup" => {
                    raw_actual_group = Some(value);
                }
                other => {
                    return path.with(other, |path| {
                        Err(path.error(super::super::codec::DecodeErrorKind::UnknownProperty))
                    });
                }
            }
        }
        let field_id = raw_id
            .map(|value| {
                path.with("id", |path| {
                    let value = super::super::codec::expect_single(value, path)?;
                    super::primitives::checked_string(
                        super::super::codec::expect_string(value, path)?,
                        path,
                    )
                })
            })
            .transpose()?;
        let mut field_extension = Vec::new();
        if let Some(raw) = raw_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_extension.push(path.with_index("extension", index, |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(value, path)?,
                        path,
                    )
                })?);
            }
        }
        let mut field_modifier_extension = Vec::new();
        if let Some(raw) = raw_modifier_extension {
            for (index, value) in super::super::codec::expect_array(raw, path)?
                .iter()
                .enumerate()
            {
                field_modifier_extension.push(path.with_index(
                    "modifierExtension",
                    index,
                    |path| {
                        super::super::codec::Json::from_json(
                            super::super::codec::expect_object(value, path)?,
                            path,
                        )
                    },
                )?);
            }
        }
        let field_target_number = match (raw_target_number, raw_target_number_element) {
            (None, None) => None,
            (value, element) => Some(path.with("targetNumber", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_actual_number = match (raw_actual_number, raw_actual_number_element) {
            (None, None) => None,
            (value, element) => Some(path.with("actualNumber", |path| {
                super::super::codec::Primitive::from_json_parts(value, element, path)
            })?),
        };
        let field_eligibility = raw_eligibility
            .map(|value| {
                path.with("eligibility", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        let field_actual_group = raw_actual_group
            .map(|value| {
                path.with("actualGroup", |path| {
                    super::super::codec::Json::from_json(
                        super::super::codec::expect_object(
                            super::super::codec::expect_single(value, path)?,
                            path,
                        )?,
                        path,
                    )
                })
            })
            .transpose()?;
        Ok(Self {
            id: field_id,
            extension: field_extension,
            modifier_extension: field_modifier_extension,
            target_number: field_target_number,
            actual_number: field_actual_number,
            eligibility: field_eligibility,
            actual_group: field_actual_group,
        })
    }
}

impl serde::Serialize for ResearchStudyRecruitment {
    fn serialize<S: serde::Serializer>(&self, serializer: S) -> Result<S::Ok, S::Error> {
        let mut map = serde::Serializer::serialize_map(serializer, None)?;
        if let Some(item) = &self.actual_number {
            super::super::codec::element_entry(&mut map, "_actualNumber", item)?;
        }
        if let Some(item) = &self.target_number {
            super::super::codec::element_entry(&mut map, "_targetNumber", item)?;
        }
        if let Some(item) = &self.actual_group {
            serde::ser::SerializeMap::serialize_entry(&mut map, "actualGroup", item)?;
        }
        if let Some(item) = &self.actual_number {
            super::super::codec::value_entry(&mut map, "actualNumber", item)?;
        }
        if let Some(item) = &self.eligibility {
            serde::ser::SerializeMap::serialize_entry(&mut map, "eligibility", item)?;
        }
        if !self.extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(&mut map, "extension", &self.extension)?;
        }
        if let Some(v) = &self.id {
            serde::ser::SerializeMap::serialize_entry(&mut map, "id", v)?;
        }
        if !self.modifier_extension.is_empty() {
            serde::ser::SerializeMap::serialize_entry(
                &mut map,
                "modifierExtension",
                &self.modifier_extension,
            )?;
        }
        if let Some(item) = &self.target_number {
            super::super::codec::value_entry(&mut map, "targetNumber", item)?;
        }
        serde::ser::SerializeMap::end(map)
    }
}

impl<'de> serde::Deserialize<'de> for ResearchStudyRecruitment {
    fn deserialize<D: serde::Deserializer<'de>>(deserializer: D) -> Result<Self, D::Error> {
        let value = <super::super::codec::Value as serde::Deserialize>::deserialize(deserializer)?;
        let mut path = super::super::codec::Path::root("ResearchStudyRecruitment");
        let object =
            super::super::codec::expect_object(&value, &path).map_err(serde::de::Error::custom)?;
        super::super::codec::Json::from_json(object, &mut path).map_err(serde::de::Error::custom)
    }
}