@213ff64a-38dc-442d-9de8-7915bbb36abc
GATCTAATTAAATGTAAAAGACATGGTGATGTGCCAGGGTGGAAGAGGGAAGGGAAAATGAATCAGGAGAAAGAATTGGCTACATGAGAAGTCAGAAAAACCAACCAAAAAATTGCATGTGTACGTGCATGTTTTTGTGTATGTGCATGCTTATACCTGTGCTGTAATGACAAAAGCTCTCTTCCACGTCCTTGAGAGACATTACTAAATGCCCCCTCAGTTCTCTAGTCATCTGTTCTAATATTTGAGCAATGGGTGCTCTGCCTCCTCGCTAGGCCTCCAATGATTGGCGTATGGCCCGGTCAGTGCTTGCAAGGAGATCTGGCTTCTGACCTCATCATTAAGAGGCAATGCTTTCTCCTCTGGCACCAGACATCTGCTGAACCTACTTCTGTTCCACAGCAGAGAATTCATTCCTGGTTCTGTGGCTTGTCCAGCCCAGCAGGGTGCAGGTGAATTGGAGGGAATGGGAAAGAAAGAGGATTCTGGTGGTCTGATGACAACAGGCAATTCCTTTCCGATTCATCCTTTCATCAGAGTGACTTACAAGGTGCAGAGTTGACTGATTCATACACTTGGACAGT
+
GEDFIMSJMSNMKIGIGHOFSHFLGGLHLJKMOJIHDBA9@8577454BESMFBDHGGE>@>?8788879ACEHHHGICOSMSKMCAADDA?530//3<@<@?BCCAEIJHKFKGEMJKSHECCBEBB@??@EGG=;<CCA@BB>=?@GHFIHFHSKGHSNMKIJJSSBCBHFSM=;=44:;;89@CGNGBDG<>?DGPHDMKJHJEFIJFGJISIHEDEFLJSIHGDHHROHGGESJIKSHMSLC=<;<ABEGJIKHBAA@CIIHJGI5446<778BE;6158DLFJJSIEHFFKESEGFIGKGIJPJISHOFDBDGIKJ?>>CIJLJGISJSKIKKJSMOSIHSSSIQKGI<::>8><<BDOGJLHPGDFLGIESSF5556MSISM9777HD8:,E;GIBDDB,+)BBDCBJKIOKKHSSNGLRSSSLSKGJKHIHGJJSQLMSIKSSGSMMCBCDBEFJIIOJLIEGDIIGAB43-==BB?>>EDGMSFISKCCCADDDGDFEB@CSGA>>>===>FHKLHGEFLIJKKJJISIHSLSSOHIPMMSSSRSJC>7.--.9CPIISHHLSKPNEG>3111-*'
@b89eab69-799c-4872-b760-0f878b192586
CCCAATTAAAAGACACAGACTGGCAAATTGGATAAAGAGTCAAGACTCATCAGTGTGCTGTATTCAGGAGCCCCATCTCATGTGCAAAGACACACATACATAAAATAAAGGAATAAAGAATATTTACCAAACAAATGGAAAGCAAAAACAAACAAAAAACAAACAAACAAAAAAACAGGGGTTGCAATCCCCTCATCACACTTATTCTAAAATTGACCACGTGATTGGAAGTAAGACACTCCTCAGAAAGTGCAAAAGAACAGAAATCATAACAGTGTCTCACACCACAGTGCAATCAAATTAGAATAAGTGTGATGAGGGATTGCAACCCCTGTTTTTTGTTTGTTTGTTTTTTGTTTGTTTTTGCTTTCCATTTGTTTGGTAAATATTTCATCCCTTTATTTTGAGCCTATGTGTGTCTTTGCACATGAGATGGGGCTCCTGAATACAGCACACTGATGAGTCTTGACTCTTTATCAAATTTGCCAGTCTGTCTTTGATTTGGGGAAACTGGTGG
+
(()+,'1--=HIFCEFFIHJGCDB???@=,,+,*+<<968:96656558=DHIHENFKIEOICA@?CJJIFEFDGMGJ=<<<<>?@@CBB?111300'&&(*&'(+-.6=3+2+**+766554454>:89<95778DBBFOKA@?FIGGSHKEFBCB=>>99EE?986<@<AGJF7348;8531.-.0/--128782369<A8:>?>=>=EMIMEJSBCE2221*++(*,/,*((+(()3126<ACFEHC?84446NSCEEIMIKKQGHHKSILSSHIEDEHJLSIKKMLLJRHSSFDBDBSLKHHSHSOOML@>91/.-)()+'(+++,586442579;43320::894/86?B9998:43:<;2/-.1/6/9;31000..//54544320,.))-(87-99?</--,,-879@DIDE@@B@=:62000.,,+-.144311/-)+1.-,-36;:9;:<>6657;>>//...07/+5,++*-1/,---10+(((+((/&%&'/*0222/-**)&&&&
@2ccdc402-afb1-4a9a-ae4d-a4c4b6daab59
CTCGTCTCTGAGTTCATTGCTCACAGAATCTATTTAGAAGTACGGGTTATTTTAGATGTTATTAGATTAACAAGATTGATTGTTGTGCTAATTCTTTAAGTTAAAAGTAAAGTTATTTTACATCCATTGTCAGGACTGTTGTAATATACTGATTTCACGAGACCATGATATCTTATGGCTGCCTTCTAGAAAAATGTCATAACAAATATATAATTCACCTGTCCTGGGAGTCAAGAATGTTAGAATAAAAATACGTAAAAATATGAATGGGGCAAAGATTGGCACAAGCTAGCGCTAGTCTCGGAGCTGGGAGGGTCCTTGAAGGTCATTCTGAGTTGGCCAAGATGTCCAGGCTTGAGGTCATTCACGGCCACCAGTCGTTGGATGTGGGAAGCTATGACCTGAGGCCAGGGGCTCCAGGCAGCTGAGGCTTCCCTGAAGGGCCCTCCAGCAGCCAGAGCAACATGTCCTCCCTTGAAAGCGGATGAGAGAGCACATCACAGCTTCCCCACAGGCTGCCACCATACCCCAAGTTGATCTGACTGAGCCAAAAACAGGAGCCGGAGTGGGAGTGGACAGATGGGATTTTTATGAAAAGAGGCTCGATTTTCATTAGTGGTAGCAAGAACTAGAGAGAGCAATGGTT
+
559778@;:67=?AOPJJIHSIDDDCHIHOSGDCCDGSSKSFEA@?>IAFIFC433::CMADHJKLOLRSINNHJFHISSGSBBBCIHGFGKJMOLLSLSJLIJLJSRSJGHEFB>::;;?ACIGDSIKQMAKGFSLSESFSKGGDBDDJHSLSDCFKCACFPSGLEJGDKFGGEGBCDFSGEB8-,-/BHNLM?MSJKHOLILOIIJGGIOGFSGSJPSSLIFLOSDOA?<<968>8:?>+9:ECDELGIKE?7769AHPS>B9;HIHSIMSQJIJEIBACFFIHDDBB55554?>?DBDIFFKJHFHMGNGJSHOMSKGOFFHKFNEISSIMIFGDDDGJGGSOSIJJHMGHSAA@AGSB@?@B?ABDEHSLFSKGCAAAJHJLLHNFFKODIFECBDGFIGONKEHJIIIKIJFKJHJGRJGIHESHBLPIKD?CCBBDAFD6D44>AC;;52111//235DKKFHFGINFDMIKKSSS=;;<264B@GHK<;;;SQHJOSDC?<EIIIDGIISGCCDSKSMJNIHJJSKJIMLSIIHRKMKIGHF?GCSSSCKSKKHGECDHIJKKKLSSHJFEDEB>F@;<<:;<42../1@@IC@9;=::9>DGDGLILMJGGE6555)&*+&&)('''(***11.%$$$
@48143e90-1957-41e7-8fab-d711b136f8aa
TGTATTCTTTGTCAAGTTGGCAACAAGGATCCTGGAAGCTGACTTGATTTAGGGATTAGAACATGTTTTTCCTTTTTATTCCTAGTCCCAGAAAATGATATCAGTGGGAATAAAATGAGAGAGGGCAGTTTGGACTGTTCCTCAGTGAAGAACAGGGGTTTGCACTCATCAGGTGGATGTATGGGCTTAGCCTGTATGCAGAGACCTCTGCATATTAAATCTCATGTTGTGGTGTGACAGCAATGTCATGACTGCCTTTGTCCCCTTGTGAGCTTTGTATCATGTAGAGTGGAGATAGCTCACACCCTCATTTAACTGGCCAGTTAATGAGGCTGCTGCTGCTGTGAAGTGTGTGTGTGCTTGTATATTGTTAAAAATTTAACAATATACAAGCACACACACACTTCACACAGCAGCAGCCTCATTAACTGGCCAGTTAAATGAGGGTGTGAGCTATATTCCACTCTACATGATACAAAGCTCACAAGGGGACAAAGGCAGATCATGACATTGCTGTCACACCACAACATGAGATTTAATATGAACAGGTGCCCCCGCATACAGGCTAAGCCCATACATCCACCTGATGGTGCAAACCCTGTTCTTCACTGAGGAACAGTCCAAACTGCCCTCTCTCATTTTATTCCCACTGATCATTTTCTGGGACTGAATAAAAGGAAAAACATGTTTGTAATCCCTGAGATCAAGTTCACTCCACCTTGTTCCAACTTGACAAAGAAACACACCATAAGCAATGGTGA
+
CNGISKQSSIHLREFABB???B?>>@?=@@A@ABEKFHKSDGDGI>==92*+**(.+'((//>?<<<:;;;=<;DDGDCB?FIABB=<=9654545?AAEDHDHIHHKPFCDSSJD689:@EHMJGLGGILLIGEKLSGHOHFBA?78GIEFCAABD?ADC><52007@<<<<EHECEIMCE=>==DC33334=<:;=<:9210-)*&&(&'()))()4A==<<JEQSGMGEGIHIGGSMIJNILQFDSAAACCSF9C<6F?AFFEE4>?@?=>>IB@))(++)*/046>@?DGEJCFFJBDEFFEJFH?@7446@BHJLMFEGGEJLIIIHFHIHHFA>5../BKDELGHFFJLIFFEADC86344591:85:NQG@<:;<<;?=CCBCD@@BCBB@A?B@==;9,+))''&''')/02126669;;;:5330.+**()3543355443*'''''(&'&&),//033>AEBCB?@?@D<76545211/-++***+-40///,,/456224?;433311279><A>>?BEACB?;9=43212239;ADBB3305==---.7865526995569989;<=<>;<94//0/../86774123778583/06<::;<;<<??=:9+++++)++,+356789<<@A854.586@=641-/11CK?<322320,&(237;:9225441.))&&(('&&&57998,*((''*&'&.**34496862)&%%$&(+++)%%%%)''%%%$%&&&%#$$$%&$%%$$$##
@16bbe65c-310e-4807-aa09-58386f8d5850
CAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCTGGGCATGGTGACGCATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGTGGTGAGCCAAGATTGAGCCACTGCACTCCAGCCTGGGCAATAAGAGCAAAATTCTGCCTCAAAAAAAAAAAAATTAAATTGGTCAAGGCCTAGGTAATAAATGTTTTAGGCTTTCCAGGCTATGCGGTTTCTGTCAAGTACTCAGCATTATCATTACAGCATGACAGCAGACAGACAAGATGTAAACAAATGAGCATGGCTGTGCTGCAGTGACACTTTGTGAAACAGAAACATGAAGATTAATAGAATATGCATGTGTTGCTATGTATCATTCTTATGTAGTTTTTCCCATCTTAAGATGCAACTTCATTCTTAGCTCGTGGGCTATACAAAAATAAGTAGTGGGCTAATATGGCCTTTGGGCTGAAGTCTGCCAATTCTACTCTAGAGACAATCAAATAAGAGCTTTAACATGAATGTTTCTGGAATTCGGAATTATCTCCACCCATAAATAGCATATTTTGTGCATTTATCATAGTTCTTACCACTTTCTGTCAAGAATCATTGTTCCCTGTCATTTAAATCAGATGATTGTGCCCTGAGAGATAGAAATGTGGTATGTACTTCCTTTGAGCACCTACAGAGCCTAGGTGTTGACTCTTGG
+
$'(++**+*)**;::<B>?:84478B@@DSDC=7214BCBCGEBDDEH???@S::900008995.,01578AA59=;AG@?>945EFGGESHHLSFSSMKFQ<<<<HSFSED>>>@EISMMLSGGJGFKJFEHEIJ@BEISH887788BECFHSSLLLESLS@HJJQIHSIFHG?DGEIABAC@@=>8404/236@SSSSJDBBBB@@7563333<;<CDEHHEKMISLSNSISLCLFGIGOEF?AC999;;85459<6654(&&:;<;<34==?ED@A=;;:;=<::6557:/5&&&989=DBEIDF?A@:;GSHDDCA?@@EENJKNLFGGMHLJMGGFF:9.*91-(%&*)*+(&%%&*'()(*+-.;=:45:658::991233AA8889>=//./?@==>=EA=66456<:<=6-9555&)&'*%%%%)--+.9=1?612?>:899DFIIIFG@>>9FLLH@;;CAB?@A>?)&%%&&'*+182*,,,/.1227.+**,+-.2,2,++&&%%()369<A;776501.14,++//0669ADFCE@@@>@;:89<?.***.20..+**,'55-)94431..../887;>1001>?C;8779F:9:::LJCCBA@==@789834448971/3)$$$$'()/0((-63+&&+*&&,521116>>@CDE889AAIIG@@EKGHSJHBSSAAA@=LGBLHD>?B@776667:-(()./.,----'#$#$&&'%&
@465edda3-b742-4076-96e9-94529f5fe7f7
ATGAAAATCTTTTCCTCAGAACTTTCACCAATACTACATATTTTTGATGAGTATTGCTTTTGGCTTTTTTAAAATTTATGTGTGTTTGTCTCTTCACATGTCCTTCAGAAGCCTTTTGTATCACTTTAACCCCCCATGGTCATCCTCAAATATTTTTGGCTTTTATAGTCTGTCTTATATAGAAAAGCATTGTGTATTTGATTTTGTTCACATGTTAACTGTGTCTCCTTACCCAGATGTGCTTATGACTGAAAAGGATGTAGAGGAGTCATAAGCTTCCCAAACGAAAAAGGATGCCAATCCCTTGCTCGCTACCTGAAAGTGCAGTTGAAGCCTCATCCTTTAATGAGTTTTCTCAAAACCCAAAAGTTTTCTTCATAACCATTGTGAAATAAAATGTATACCAGCCTGGGCAACATGGCAAAACCCCATTTCTACTAAAAATACAAAAAAATAGCTAGGTGTGGTGGTGTGCACCTGTGGTCCCAGCTACTTGGGGGGTTGAGGTGGGAGGATCACTTGGC
+
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
@d007de7d-acc6-42d6-b918-c15b7222dc8b
CAATAGATGCTGAGAAAGCTTTTGATAGGATCCAACATCCGCTCATAAATAAAAAGCACCAACTAGGCATCAAAAAAACTTACCTCGAAATAATAGAGCCATCTATGACCAATCCACAGTCAACATTATACTGAGTCAGCAAAAGCTCAAAACCCTTTAGAAGTGAAAGAGACCAAGATGCCCTCTCACCACTGCTATTGAATCATGCTCAGAAACCCTAGTCAGAGCAACCAAGCAATATCAAAATAAAAGGCAGCTGATATGGTTTGTACTCTGCCGCTCAATTAAATGTCAAATTGTAATACGCAGTGTTGAGGGTGGGGCCTGATGAAAGGTGGTTAGATCATGGGGATGAGTTTACACCGTGCTGATCCCATGATAGAGCCCTCAGGAGATCTGGTTTCAAAGTACGTGGCACCTCCCTCGTCTTTCTTCCTCCTTGCTCCAGCCAGGTAGGACATGATGCTTCCCTTTCTGTACTGATTGTCAGGATCCTGAGGCCTCCCAGCCATGCTTCCCTGTATAGCCTGAAGAACCATGAGGTATTACAGTTTTAAAGTGCTTCTGGATTCTATTTGCTAGTATTTTGTTGAGATTTTCAGTCTATATTGGCCAGGATATTTGGTCTGATTCTTAAATTATGGTCTTATGCAAGAACACACAGTGAAGGATCAACATATCAAAGTAATATAAGCGATGGTTAT
+
&)13?BCHIOF8778HIGKHA=<;6500058=::>?AMB<355866)(((&&%)*)(''))))*+++,/21155789?.,,,5::>>?@IA---*%&)*--40--.,-->?DGCE9?;<>65334::;D<9878::((((BCCE627,+12;9:7776+***+3-,--,0('00/17CAB@?HGGIFFPIHHKSLFE>=21/.,,,)()(('(-78;<=*&'89:;=?FGFDCEFEDFDGFF@@@51()286778878.../CAABDOED?;9*''''&)))(/&////8@?.../FIFSGEFOECGFEKJIHC@AACE?>?A:749:;::;FJKI====?=;;(&&&&1241''&&+&&'*/,)*001////5/++***-)))+789;35EHGSSKK=<:=>9224;:::==;;=?B@?;;;;523457..0/--46/0*'&%%',.01199;@@>>>771112341./24798;9999:22561/,+*)*)))-**,+*/;::6,-,1--*)+*&&'&4544=<<=?>@CBDD@@@@87774-,+'%###%&'%&,7777;;;=<877954-,-(')&&/0/,,,0-,*&&$$$%(*)&&$$##&&%'###%()((+,100('&&&'%%%%*/(/,*...*((''(%&&(-.45766:6554-))).--,)&&&()&&$$$$$$#$%%%$%%$###$%#"""
@8d6ab343-f9e5-4610-b1de-d16faa3b14a4
TTGTGTGCCTTCATTAGTTATATACTAGTTCCTGATAAATTCATTTATAGAACAGAAAGACCACAGATTCAATTATATGGAATAGATCTGCTGGTGAATGTAAGAAAGTCTTCTGAACTGCGAAGGGAAAATAAATGATTTAATTCCCACCACCTCTCAACAGCTACCTTCTGTTTTAGAGACACTGGTAAAACTTCTGGGGCTCTTACTTGACATACCTACATCGTATTATAGGCCTATTGGTTTTATCAGAATAATATGCTTTCCTCACATAAGTTATTTCTTTCTGTTACTTGCTTGCAGTACAGATTTAAAGGGGCATTCAGGCAGCCTCCAGATGCCATGATGGATTAACTCTCATGTTACACAGTAATGTAGAAGCTTCTCTTCATTCTCAGACTTTATCTGACAATGAAGAGAAGCTTCTAATTATACTGTGTAAGTTGATCATGTAACACATCTGGAGGCTGCCTGAATGCCCCTTAAATCTGTACTGCAAGCAAGTAACAGAAAGAAATAACTTATGTGAGGAAAGCATATTATTCTGATAAAACCAATACACCCTTATAATACGATGTAGGTATGTCAAGTAAGAGCCCCAGAAGTTTGCAGTATCTAAAACAAAGGTGTTTGTTGAGGTAGTGAGGAAAATAAATCATTTATTTTCCCTTCGCAGTTCAGGCAACACTTTCTTTACATTCACCACCAGATTCCATATAATCTGTGGGAGTCTTTGGCTGTTCTATAAAATGAATTTATCAGTAAATGA
+
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
@a4dcc2ac-e840-4c8f-8953-f6f28376eaa1
GTGTTTATCTGATCAACTCTCAATGAAGGGCTTTTTAAAATTTTAACACAAATTTTGTAGCATTCTATTGATTCATATTTTGATTCTCAAAAATAACTATTTCCAGGTTGTCCCTACTGAGTATTTTGGACTCGTATATTGAATGGAAACTCAGGGAACACCACCTGTAAGAGCAGGAGGTAAAGGCAGATGCGAGGGAGGGAGAAAATGAGAGAGAGAGAGAGACAGAGAGACAGATTCAGAGTATGTGTATGTGTGAAAATAAAAATTAATATTTGAGCTAAATTTGTAGCATCGAAATATTCACCTGGGAAAGAAAGCTCTAGTAGCTCTCTACAATTGCTTGTGTGGGCAAAAGTTTTAGAATGTACCAAGGCTTTTTGAAATCCATACCTAAATTTGGTCTTCTTCTTTACTCTCCTCTTAAAATTGCTTCATAAACAGCCTTTTAAAATTTATGGCCCAGTGCGGTGGCTCACACATATAATCCCAGCACTTTGAGAGGTTGAGGTGGGAGAATCGATTGCTTGAGGACAGAAGTTTGAAACCAGCCTGGGAAATATATGGAGACCCTGTCTTTACCACCTAAAAATTTGTATTACTTCCCGTACCTTGTTTTCCTAATCTTGAAAATGGACATAAC
+
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
@5e48c319-86fa-41b7-97d9-4844b505ccf2
ATGTTTTTGTAACACCTTCGTTAAGAATTACGTATTGCTATATAATTATTACAACAATTCTATGAGGAGGTTATTTTCATCCTCATTTTTGAAGTAAAAACTGAGGCATAAAAGGAATAAATAACTTCTGTAAGATCAACTGCTAGGAAATCATGGATCTGAGGCTTTAGGCTATTTGAGCCAAAAATTGTGCTTGATTATCTCCAACATGGGAATCTCCTAACACAGTGTCTGGCATGATGAGAATGTCTAATAAATGTCAGACTGATTTCTCTTCTGTAGGGTCTCATTCAGAATATTATCTGAAGTGAGATTGAGAGTGGTTGGCTCCTGCAGAGATGAGGTCTTTACTTAAATATAGAATGAATTATCCAAATATGATATCACCAAACAAAATATACTCATAAGAACCTATGCAGAGAAACTGAAAGATTCCTTGCAAGTATAATTAGAGAAGGATGCAAAGATGAGACAACTGATAAAGCTGTATTTATCAGAAAATGGGAAAAGCCATATTGTTTTTGATTTCAAATGTTTCACTGTTAAACACTTACGTATCAATGCTTTGAAAGCATAGACGCTCTAATTCACAGGAAACACAGTAGTGGTTTTAAGCAGAAATACAACATTAACATTAGAGTATATTTCGTTGGTGATATCATATTTCTTAACAATCATTCTATATTTAAGTAAAGACCTCATCTCTGCAGAGCCAACCACTCTCAATCTCACTCAGATAATATTCTGAATAAAGTTAGAAGAGAAATCAGTCTGACATTTATTAGACATTCTCATAATACCAGACACTTTGTGTTGAGAAATTGCAGTGTTGGAGATAATCAAGGCACAATTTTGCGCTCAAATAGCCTAAAGCCTCAGATCATGATTTCCTCACAGTCTGATCTTCATAAGTTATTTATTCCTTTTATGCCTCAGTTTCTCACTTCTAAAATGAGGATGAAAATAACCTGCCTAGATGAGAATTGTTGTAATAGTATAT
+
%&)*))))((&$%$%&(*&%%&&&''(&&')-.3442----<<AA;D=55223377::;CB@?98789CFLFDEFFOFDFD?7<<<;<<4*&&-.(''*66467=?;>AC@>>@@6=:44343212/(()))*21,(,+45??@?BABCC?64434:>;:88?CAA@?3234??>>?433255<EF8//--.-,,+++)''(())==<>GHEGGEA1000BCGGFFEFSLGE@AAJML@@A??=<<=<=:9877.-17/0.///343555427,,=27221164544)'))))118:53325777BCBD<00;++8:<ACCAEIFIEEFA@@@50444554899;9::>8;<>4KEIIKECCEE//.-0*-&%%$%,''&&..002344=98'&'*.*))*-&&&/*'(-()50/,-...,-.-,.435;<533.---'&&&))&&&(,/'&&&&-*,,*''((13HFDBCBFGIJFB@AAHSLDIFDG?C@33-...)))*>>=@:555-'&%%+($$%%,5''++,-6754865,(//6470--?@:::;>GEGEGGIHSSFGESEGFIE><;2112((((())4;7>AAAA>FJEDF;;;544..//8<74423443479:99:4333DNIFI@AAEAAC@==>;:<70HKEJINKEHEHDJFFOM?BSHSSGSSS;;;;G@JKCB?@EBFHB==?:754511266433200--//6:9;0///--''))%%((()/*-((((2246;99884-***+588=<;/--.87--+''(,()(&,-/...+,(&%&''%$$&110151*)'*0/1&&%&'),0)'%%%'')'0,,(&&&'&&&((()-./-/3:,*(')*/1240/./2(&'''((''%%%$$&%%$%'&&&$$%)0100///...**,-544A@ACA236-3222200*'&'+-..././,*+0126,-=E@;:9853,+++*,13444.-)&'+,.--,,.02***,33240,,,-/.
@7329abb9-687f-4b86-be63-054cea54c9a2
CTAACAATGCAGTTTTATATTCAGAATGAAGAAAAAGAGAGATCTGGGGGACTCAGGAATGGGAATCATTAAGATAGTCTCAGAGAAATCATAAGTGAGCCAAGGATTTGAAAATGCTATGGAGATACAAGTGCCCTGGCATAGCTGACCACGGCATTCTAGCAGTGGAGAGCACTAATATAGGTGCCCCTGCTATGTGCTCCTGAAGCATTCTGTTCTTCCCTCATCATTACTTTGCTCACAATGCATTGTAATTACTTATTTAGTGTCTTTTCCCACTTGGCCATAGTGGTCATGGGAACAGGAAATTGTATTCTCTGGCTAATTATTGTATTATCAGCCCATAGCATAATTCAATAATTAGCCAGAGACACAATTTCCTGTTCCCATGACCACTATGGCCAAGTGGGAAAAGACACTAAATAAGTAATTACAATGCATTGTGAGCAAAGTAATGATGAGGGAAGAACAGAATGCTTCAGGAGCACATGAGGGGCACCTCTGTAGTTGCTCTCCACTGTAGATGCCATCATGCAGCTATGCCAGGGCACTTGTATCTCCATAGCATTTTCAAATCCTTGGCTCACTTATCATTTTTTCTCTGAGACTATCTTAATCATTCCATCCTAAGTACCCAGATCTCTCTTTCTTATG
+
-/78CDGSCECCIAFIDHOFGEEGFMS?A?A9:CDGC@ADBEC??>@EGH?777BCCCOKFIDGGFDDDFIGFHL@33==534.-,5;6999:<FSPSJLGHSHSSGSSGJSLNSECDCEDDHSRSOMSHRMNIMNJSSRKJRSFIEBDCAA<<=?SE?=222227311<<55548.---.,,-.124445?DKGHGMSRSLSSGGFFOJSO;;;9<38>=E?;8777=HGSHHSNHGSSJSLSHEEEFGJSIHPJSHHH@GIPAINKLOSHSFPF?5FHHRGPLJMFIHFDDISFIIGSC?7467:A@>==?BFBA@@IHEEHESKSKKKGGIFGKHIJJESSLPGSJSJSSJHHSNMLFME@B@=80./1/..67:FA=;=;;696231,,,.'&&'/012432.,-/12540*)(((&'')*++-++,/027>BBB@A?97+((%''--1459>A?==<><4@>==87755100,++058762132*$$$%)11///.,*+-.(')'&%%&%((+)'&$$&*&(('.,++(&&&&--38995535243-,++127776559;::;<=@60/00*))+&''')&%&'..&&&&('+43/++2138874422/*-<0///61&(222*('**))))174332151/500-&%%
@2ecc0ab6-6c24-4315-a114-f13bc7d6f8d5
ATTCCAGTTCTTTCAAGAAGCATACAAAGAAAACCCATGCAAGCAGATTATAATTCAAAGCCAGGAGGAGGGAAATGAATTTTACTTAGCAATTTTGTGCCAGGCACTGCTCTAGATACTGGGGATATGTGGTCAACAGCACAAAGTCCTGGCCTGCCAGAAGCTTATACCTTCACAAGTAGTTTAGATCACTTTAGAGAATTTCTAATAAGTGCTAAGATAATATAATATGCGAGGTGACTGGAAGGCTTCTTTGGCTCAGAGGATCAAGGACAACTTCTGAGAAAGAAACACTGGAATTGTGACCTAAACAGCACGAAGACAGCCATGGGAAAGACTGGTGGAGAATATTCCAAGGTGAAGGAACAAGAGCTGAGATGGGAGCCTGGACAAGTTCTACAGGAAAAGCAAAAGCACAGTGGCTCACAAAATTGCTAAGTAAAATTCATTTCCCTCCTCCTGGCTTTGAATTATAATTACTTGCATGGGTTTTCTTTGTATGCTTCTTGAAAGAACTGGAATAGCAATCTGGTG
+
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
@7a0b557b-87f7-40a5-85ee-ad35b018d1ef
CATTCTCTTAATCTTTTCCAGTTTCTCTTTTCTCATCCCACAAAACAGGGATAATAGTACCTGCCTCCCATGGCAGATGTGAGAATTAGAGATCATGTGTGTAACAGCTACAGTGTGCAGTGGAGAGTAGTTAGTTGCTCAGCAAATGATGGTTATTCCTATTATCATTAAGTTAGAAAGCTAAATAATTGAAGCAATTATAAAAGATACGTTGAATGACAGTCCAAAATACTTGCTGAATTCATGGTTTGAAGTGTCAGGGACTTTCTTACCTATACATCTTTCCTGTGGTTCTCACTAGAGACCTGGAGGCACGTGTTCATGAGAACACTGAGGATGGAGAGAGTGAAGTGGAAACATTTAATTTGGACATTTGGAAACATTCAGTAAGTATTTTGGACTGTCATTCAACGTATCTTTTATAATTGCTTCAAATTATTTAGCTTTCTAACTTAATGATAATAGGAATAACCATCATTTGCTGAGCAACTAACTACTCTCCACTGCACACTGTAACTGTACACACATGATCTCTAATTCTCACATATGGGAGGCACTGTGTATACCTGTTTGTGGATGAGTAAAGAGAAACTGGAAAAGATTAAGAGAATAAAGTGAGTGGTT
+
*26758759-/EBBBDEDF:@=>DSB=62;3**)++((+%006<;::BBAAA0//+**)+++66766685DC@@ABDECB<878:>>43357543334@@@?BBADFABABEGFIJJIEDB90+-('()&&)''((+---477ACFJCCB>?;55563>=4465=CDKFHJEEDDDHGGE8657@FD@?8/@CDCCAIHSLKHGPIFCDBAAB;<<<IHJKLIEIDDHKFIKGEDCFEDBAEBCB?A@BGBC@BFJG?>=ADND>G85=924?666>?HLEFG@8>1?CBDDFDCDBB=+*+.,+,0'&%$#"#%%&').)*/0<<?@>@BD6467555//01/*&%%*1)((+3;HIPHJB>FB82223FHEHDCDDGHHHFC=?=9,++-9766671)):;<65568222(&&&(&&+?>FCDH>9999:9787<9656689996*))):999AE>>>0//0666EBLSLGKFMGSGD;:9'&'-8889;<@CEBBDENSGGLEFFFEDDAA-,,-12./466599722002301:<66...*++,-.25/,*(&&$%$$(*****86777;<>8A>:93.,,,*('*'&')/13844*))()'(&%&&(&&%$#$$$%%&'
@1eb0cb68-d6bd-4af8-aedf-dd2586ea09a5
TGTTATGGTGTGCTTGGTTCAGCGTATTGCTTGAGGCTGGGAGTCCGACACCAGCCTTGTCAACATGGCAAAACCGCATCTCTACTAAAAAAAAACAATTATAATACAAAAATTACCTGGGTGTGGTGGCACACACCTGTAGTTCCAGCTACTTGGGAGGCTGAGGCACAAGAATCACTTGAACCTGGGAGGCGGAGGTCGCAATGAGCCGAGATGGTGCCACCGAACTCCAGCCTGGGTGAAGGAAAAAAAAAAAAGAGAGAGAGAGAGAAAATGAAGCAAAGAGACTAAAAAGGGCCAACCAAATTTGAATTTACAAATGGAGTATCTTCTTCAAAAAATAGAAGAAAAAAGTTAAATTAGACATTGTTCTTAGGTGAAAATATCTGCTGTCTCTTGGATTTTTTTGTGTACACAACAGGTGCCTCCCAACAAAGAGCTAAATTTGTCAACATAACTGCATTGCTAACTCTACTAAATAGAAAGTGCGCAAATATTTTTTGTTCTGGTAAAAAAAAAAGCTTTTTCTTTCCTTTTTTTAAATTTTATATTTTACATTTTTAATTAAAATTTGTTTTTCTTTTCCTTTTATTTTGTTTTTTAGGGATGGAGTCTTGCCATATTGCCCAGGCTGGTCTCGAACTCCTGGACTCAAGCAATTCTCTCGCCTTG
+
$%%%##$$&&'&&$$$$&&&%$$%(/115:><78EJGB:9:CB@>?=>?@GCEMGFISFDC>?DJJGECCEFNHHCAABFFGKKID?=DLSSSSHSBBCCSDDCAKSGSFSOSHDEHFEEECDFDGLBEHBCCBECEEHJDADCEOKLIKSISPGKFLSGLHDDIHHGSJEFIQJLIHLHGHJKKLMNLLJFFDDDGDF7666DIEGIHPGHFIEDB@ADEFGFBEECLLMOJQIJSHNGHSHB:6=CACGGILDF<9<BMPSSNLGGFEDLSHB;;<?A<9>GSGCNC?@ASLBGHDJFHD?@S@9BA@ACCSJJQISKHDGFGEFFMHSGJJAGGCJ::;C=>EGJHSKSRDA@8??DDFNNGRFJISJ=BD667IGEDIKGIICDB@DCCFEEA@7IFPFDEJGHHGGGIHFEEGCDHFFBEDEDEE9999EHISLEFJFFISIISGJEHFGDJHISGJSLHFBBCKPKGGCEHISIGJJKKKJ=84337:@988:=GIGJGADC>>>CJLIDFFDIJEG@LNKEDCJB@<:SKSSSFSGEFILIFCAEHIIDCCCHKHEFCFGHILIRLEJ<KSSE99IKI887HC?@DFIDD<GIOHEEABDDGHGIOFD?>?>AFIHHFFGDBSNIGJHSJNEBABHOJESIKBCCBGGF>,,,-A<85756@DIG
@081572a2-5b55-4384-92d2-7de1959adfaa
TTGAGAAGCCTCCATACTTTTCTCAAAAGTGGCCGTAGTAATTTACATTTCCACCAAGAGTATACAAGGGTTCCCCTTTCTCCATATCCTCACTAGCATCCATTATTGCCTGTCTTTTTTATAAAAGCCGTTTTAACTGGGGGGAGACACCAATCTCATCAGAATTTTGCATTTATCTGGTGATTAGTAATGACATTTTTTTCATATACCTATTGGTCATGTGTGTGTCTCTTTTAAATGTCTGTTCAGATTTTTACCCATTTTTTAATCAAATTATTTGGGGTTTGGGGGGATTATTGTGTGCTATATATATTTTCATCGTTGAATATTCTAAAGAAATGTTTAGTATTTATTATTGTCAAATTAAATATTTATTTTATCTTTTTAAGAGACAGTATCTTGCTTTGTTGCCCAGTCTGGAGTGCAGTGGCATGATCATAGCTCACTGTAACCTCGAACTCCTGGGCTCAAGTGATCTCCATCTCAGCTACCCAAGTAGCTAAGACTGCAAGGCATGTGCCACCATGCCTGGGTAGTTTTAAAATTTGTTTTGTTTTGTTGTGTTTTGTCTAGCAATTGGT
+
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
@135b593f-a045-4d95-bcc8-e6d3a10e0053
ATGTTCATTACTTCTTGGTTGGTCTTGCTCATACATCCTGGACTTGGGGTAGGCCCTAAATCCAGTGCCAGGTGTCCTTAGAAAGGAAGAGACTCAGAGATGGTCCTGTGAAGACAGGCAGAGATGAGAGTGATCCTGGCCCAGCCAAGGAACATCTGGAGCCATCAGAAGCTAGAAGAGGCAAGGAAGATTGTCCTCCAGAGCCTTCAGATGGAGCGTGGCCACTGAGTTTGTTTCTGGAAATTCTTGTGTGTATTTGGACACTAGTGGCTTAGCTCAGTCCTATGCAAAGTGTGGCCTTTGGTGCAGACAGCATAGGCATCACCAGGGAGCTTTTTTATAAATGCAGATTCTTGGGACCCATCCCACACTTTGCATAGGACTGAGCTAAGCCACTAGTGTCCAAATACACACAAGAATTTCCAGAAACAAACTCAGTGGCCACGCTCCATCTGAAGGCTCTGGAGGACAATGTTCCTTTGTCTCTAGCTTCTGATGGCTCCAGATGTTCCTTGGCCTGGCCAGGATCACTCTCATCTCTGCCTGTCTTGGCAGGAACCTCTTCCTTTCTAAGGACACCTGGCACCCGGGATTTAGCTACCCCAAGTCCGGTGACACAATGT
+
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
@2d58d30e-929a-4e19-8a71-de487b23e690
AGATGTGATTTCGACTGTTGTATCAAGAAGTTGAAATTATGTATCTAGAACTGAAGGTTGAATTTCTCCTTCATATCCCCTCTCAGGAACAATATCAGCTCCAGAAAAAAATTGAGAAAAGTAGAAAATCCTTCCTGAGAGAACTTTGTAAATCAGGGACCTAACCTTCCTAAAGTTAGTATTTACTTCCTCTCAACATTCTTTGTTTCTTTTCAACATGTGTCTGTCTTCCTATTTCATTTTGTGTCATTGTTAAAAATCCAGGAATGTAAAAGTTCTTCATAGAACACTTAGTTGGCCGTGATCGGATTATTTCTGGTTTTCACTTCATGTTCCCTTCCAGGTATTTGTGGAAAGGGGTGAGTCTCTTGTGGAGAGGCCATCAAATGTCAGGTTGCCAAGCAGCAATCACTTTTGCAAACTATTTGGAAATACCTTGTGTTTGAACTTCTTGTTTTGTGCCGTGAATCCCCTTCCTCCACAACAAGGACTAAAGCAAGGAGCTGTTGTTAGATGTCTTAATAGGGATGGTCTTAGAATGACACGACAATTAGGAAAGAAAAATTTACTTTCTCAATTTTTTTCTGGAGCTCAGATATTGTTCCTGAGGGGATATGAAGGAGAAATTCAACCTTCAGTCTCATACATAATTTCAACTTCTTGATACAACAGTTGAATCACATCT
+
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
@6c76aefc-0af3-4001-b9bb-9214cb9008e5
GTTATGTAGCCTCGGTTCAGTTAGTCTGCCATGCCATGGCTCACAACAGCCACCCCAAACTATTCCCTTCTACCCATACCTTAGCAACCATCATCTGACAAGTAACAGACACGTTAGGTGACCCAGGAGGCACCTTTCCCGCCATCTCTCCTCGCTAATCTACCTCCCAGGAGGCTCCCACCCAATTCCCTTGTCTTCTTGTCTCTGAGGCTTTTTAGAGGTCAGGGGAGGGGGCGTCCTCCCCTCTACCCAGCATAACTTGGTTGGGTGCTGTGGCATGGACCTTGCTTCAGTAAGGAGATGCCCTGTGCCCTCCTGCCATCCCTAGTTCCAGGTTTCCTTTATTCTAATTTTCTAGCTTGATGAAAACGTTGGCATGTTTATAGGACCACGAATAAAATGCAGTGAAATTTACCCTTTTGCATTCCCTGAAACAGTCAGCCTGTTTCCTGAAACAAGTTTCCTTGACCTTTGGACATTCCAGGATCACATTTCCCACCCCACGCTGCCCCCACCCACTGGCTAGCTGATCCTTCCACTGTGCTGGGCTAAGGCTATGCTTACGTTGACATCACTGAAACCCTACGTGCCAAGCTGTGCATAGAGGAAGGCAAAGTGTTCTAGGAAGCAACGGAATACAGGTGGTCCCTGGTGGCTCGGTCTGCAGGTGAAAAAATGCAGGTGGGGTTGTTTTTTTAGGGCTCAGCAATTGG
+
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
@4193f4d6-7fe6-415b-b030-01e02bd186e4
GTGTAGCCTGGACCGTTACGGTGCTTGTTCCTGTAGTCCCAGCTACTCGAGAGGCTGAGGCAGAAGGATCACCTGAGCCCAGGAGGTCAAGGCTGCAGTGAATTGTGATCGTGCCTCTGCACTCCAGCCTGGGCGACAGAGCAAGACCCTGTCTCAAAAAAAATTTTTAAATGGCCCCAAGGGATTTTGTATTTCCTGACTTTAAGAGACAGCCCTGCCCGGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGACCACAAGGTCAGGAGATCGAGACTATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCAGGGCGTGGTGGCTCACGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGCAGGAGAATGGCGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGGGAAACTCCGTCTCAAAAAAAAAAAAAAACTTAGCCCAGGGAACCAGGGCCCCAGAACCCAGAGTGGGAGAGGGCAAAAGCAATCATCG
+
##%%%#$%'+*&&)''((($$%%$$$&**)**47+**),-,++*&%%%''(059=;3222><===<<96(&&&(//67;;970,+43*&&&(0111989555)''(,,38788:<3222BMSKIGKSFNLJJG@??>HFDCCGKGHS@ID=8776579AA?>>>:86?456:76578<:897*.((70--((+),++&&..30*.,2??ADBAA><8775++*,9=8886:9:<;;<?@A;:89@..6.CEHJHSSESMKMEHECCCDK<<<=@<;....<:9;E?DSKSSSSC7667>850/9;@ADSHECBBA=A:@AC?///0CHEQKSJSIHJIC?;877>IKN?99:?0/12+*)))8+++*&''**.0?@=:;;<LIFHKGJGEEHEDEDCFBACAC?CA>;@>BEDINESJBAABIDDD7421973.../54227HGHFSLSMFPIIQLJHEFDGCEBDSIKNSHGIBHA@@;==4:..78/.1112EE44458349BDB@>==??80/*(&&'&',/286585<331128==.'&'*5>=511275;;32.,+*'''''(+++&$$$$
@6826ae55-5178-41b3-b545-2e6c2327f01a
ACACACACAGCCCATTGGTTCAGTTTCTCTGAAAAAGCCTGATTTAATACCTCTGCAATGCACTAATTAACCATCATACATTATATTTACCTCACATTAACTTACATTCTTTACAAAACAACCCAAAAGGCCCAGAACCCACTACTGTCCTCAGCATGAGCGGAAAAGGAAGTCCAAGCTGCCTCAACAATAATTCACAGACCTCAGGGAAACCTTCTGATCCTAATCCCTAATATTGATTCCTCTTAGCCTTGTTCTATTCTCCCTATAAAAGAAAAGCCTTTTCCCGCTTGTTCCTTAAGAAGTTTGCAAATCTTTTGTTTATAGAATTTTTATTGCAAAATATTTTCAGTAATTTTTATATTAATTCCAAGTAAGTTTTTAGTTGACAATTTCCTGGTGCTGCAATTAGGGATCAACATTGAGTCTGAGCTCTGAAACCTTGTCATTCTTGACCAGGTAATGGAAACTTGCAAATCCTTTGAACTCCTTTTATCTTAATTGATACAGTGAATTTTTGGTGAGGCAGCTCTGCATTCCTTTTCCGCTCAGCGCTGAGGACAGTAGTGGTGGATTTTGGGTTGTTTTGTAAAGAATGTAAGTTAATGTGAGGTAAATATAATGTATGATGGTTAATTAGTGCATTGCAGAGGTATTAAATCAGGCTTTTCAGAGAAACTGAACCAATGGGCTGTGTGTATATAAAGCTCGTGGT
+
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
@6a4d62ce-ab7c-45b0-b32b-e1b2140c59a1
ATGTTTATACCTTTAAACAGTAGCCATGCCATGGCAAGGGTAAAAACAACTACAAATGATAGAAATACATGATTAATACTCTTCAAATTTACTATTATAAGAGAAAATAAACATTAGATTATAGCCCACTGCCTACCATATTATATGTCCTCAATAAGGTGTCATTTGTTATGAACTTAAAAACAGTAAGTAACTTTTATATCTAAATAGGAAATATTTTTTAAAAGATGGCTCTCCCGGCCGGGTGTGGTGGCTCACACCTGTAATCCCAGCACTCTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCGCGACCAGCCTGGCCAACATGGCAATACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGTGTAATAGGACACGCCTGTAGTCCCATCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCGGACATTGCAGTGAGCCGAGATTGCACCATTGCACTTCAGCCTGGGCGACAGGGCAAGACTCCGTCTCAAAAAAAGAAAAAGAAAAAAGAGCTCTCCAGCTTAGCAAAGATAAAATGACATAAGCCTCAGCTGGAAAGAAAAGAGTCATGTAACTTAGTAAAACTCATCAAGAGTCATTAGAAAGTTTAATATTGACCCAGAAATCTATTCTAAAGACACAGCAAAACCTAGAACATAGATTTCTGTATA
+
#$&'%$$$#$&%'+&%%%'&&$#""##""##""#&')&*,.,)*4:9:;>=>>DSNSLIFLFIGLKQLFEHHEEHGFNDE?<>8FSQMJPIJJCJIFPHECCLGKSMIGMCBCCDBBBACGH;::9;96668CECFEFEHJIJIGCGGKIFGFLISISMGMSILNSQHSLFG>==<82*+>=G9---FSKILGNJSSSJGJNMH;:9;B<;<SJEIGC=ASHEDHSJKG@?@FEEB@4(((()((*EFDFDIHFGIFECDGISHHLMSSIGLGHGQBBACHKSKKPHHISHDDGHMHKLISSFEDJIJSISNSS<CDA@=<=>GSBE@JEBMHMOKKHGHC<<8999@GAAANMSSJFJSSSLSSISSHMSSSCH?>>>FFSHDGAC@@B3324<=SGHEFC@A@BCDC@?<9;;NHGIJSEJKSCFFSHLJGSDHEEKHHSSGECDFHLSCABBBACEHKEEGHGSEEEDRSOSSMLINGSMFJSG@@@?JHGEDSL5555C2222:;<SNIC>>>?>8:78II=@79ECD?==BFFGFFKEGKGGGIJDDCBEDFLNSNSHMMLKLSSKMGFHBDIDLFEFGFJIOICIIGIEFFIGSHFHDFEB*****<CE733454455RI=>?@667=?>=<8(&&'''&-:<@=EKIMFFEA7538558FE:::DFHGFKNHCD<<?DCCESHIFIEAA;8440
@1f547502-ba37-47ce-84f9-2c07f0a596c7
TTTATCTTTTCTAAAAATATGCAGTTAAAGAGTGAGTTCAAAATCATGAACAATGTTAACTAGGCACAAAAAACTGGACTCAAATAAATTAGCATTGCAAGTAATTCACAGAAATTAGTGCATTGAATAACATTAGGAGAAATTCACATTTTATTTATGGGTTGGGTAGTGGTTCTTTCCAAGGAAAATTTGTAACAGTGACTCTGATTGATCTTTGGTCCTGAATTTCTAAATGCAGGAACACAAAAGGTTGCTATTAACATAGCCTGGGGAAGAAGAAAGAAACTAACAGAGTTTCCGATATTGCTCTGTCTGCACTGATATTCTGGAAAGCAAGGAAAAAATGGAGGGGAAGGTACAAATCTGCATTTTTTCCCCAACAGAATGCCTCTCCTGCTATTTTCATTTAGCCCCAAGGTTTTGAGATCAATCAGAGTCACTGTTACAAATTTTCCTTGGAAAGAACCACTTAAACCATAAATAAAATGTCAAATTCTTCCTAATGTTATTCAATGCACTAATTTCTGTGAATTACTTGCAATGCTAATTTATTTGAGTCCAGTTTTTTGTGCCTCATTAACATTGTTCATGATTTTGAACTCACTCTTTAACTGCATATTTTTAGAAAGATAAAGCAAATGGTT
+
33<7=;::=;//09==854477><;;;CCISIGDBDDNIHHOSSKJSHSLGKGEIJFLGEIA@???B@<CHGFCF=<@@IIJKSNSJGKKIISJIJPPJKMPHHSNEEFGGLHHEFDEEABCEG@A@CISJEHE@B=AFGJGLLJLOLOLMLSIHCADDGFS>;;;CBBABCGDFHIHEIHISRJGKNIGJILJFIJSHMNHSJIDDC=3;;AA?=;@AIGGFIC@BB@DDFFEGHFGSMJGDE6678<;=755::;F@@?::----400---+,)('%*/9:=BCDEFKG;9<;=4/0+358<;8787889=>><>=GDESGSHMGMBSKHIA@><9:9<B:86433>ABBBCHIIDDA?DDABA>??@@A@=3370---3489<CB@@:::CFECFFKLSMDEMFFIEE1FEGHSIFKGG(()HIC@CBEGDCCEC?B@ABB@@FJSINSHGHK>221145)&%%%%%%%%&11/=::<>@***0>@21114?,*('(-8?CJLMFJMHSSINLLGG@?=B8888:BA@>A<6569AEEFE6667BMFEJ@MKJNFHIFGSRCFGSKS??<7''))+=?BJC@BD>A?>???HGEGSGHOPJMHHPEDFMIHNOJJSHPIF0,,-70)&%&&&(((*))))&
@df8397f1-4bf7-46ac-963d-fc5ce44d81b6
ATGTTGTGTGTGCCTCTCTGCTTTGGTTCAGTTCAGGTCTTGCTTGTTGTGTCTGTAAAAAGGCCCAAGACAATGGATGGTTGGATACAAAAAATAAAAATAAAAAAGCCCAAAGAATAAATTAAAACGTAACCCAGGATAGGCATTTGGGGATAGTAGGTGTGTCCTAATAATTAAACCAGGTGATCCTTACCATAGACCTACAAAATGGACAGACAAAGATGCTGAGACTTAGAGTGGTTAAGTGCCTTGCCTAGGCTCACACAGCAGGTTCATGGCATTAGTACCAGCACCCAGGTTGTTTTTTACTCTAACTCCTATATCCTTCTTAGGACCAGGATGACTCAGATAAGAAGCCAGATGCTCAGACAACCCTGGAAAGCAACTTTTTTTTTTTGAGATAGAGTCACACTCCGGTCGCCCAGTGGCACAATCATGGCTCACTGCAGCCTCAACCTCCTGAGCTCAGGTGATCCTCCCACCTCAGCCTCCTGAGTAGCTGGCATGACAGGCACACACCACCACACCCAGATTAATTTTTTGTATTTTTAGTAGAGACGGTGTTTTGCCATGTTGCCCAGGCTGGTCTGGAACTCCTGGGCTCTAGTGATCTCCCTGCCTCAGCCTCCCAAAGTGTTGGGATTACACTTATTTACTCACTCCACAAATTCCAACTTCATCCTAGCAAATGGT
+
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
@29fba717-c541-480c-9e30-dd9e705c4565
TAGAAACTCTTCGTTGATATATATATATATATATATACACACACACACACACACACACACATATATACACACATATATATACACCTTTTTAGTTTTAAAGATGTGGCACAACTTTGTCCTTTTGCTTGCATTGCTTTCAACAAGAAATCTGTTGTCTTACCTTTGTTCCTTTGTAGATAATATGTCTTTTTTCTCCTCCTCTGGCTGTTTTAAGATTTATCACTGGTTTTGAGCAATGTGATTATAATGTGTACTGGTGTATTTTTTTTTCAATTTCTTGTGCTTAGGGTTAGTTGAACTTTTTGACTCCATGGGTTTATAATTCTCATCAAGTTTGGATATTTTTGGGTCATAATTTTTCCAAACTTGATGAGAATTATAAACCCATGAGAAAAAGTTCAACTAAGTTTCTAACACAAGAAATTGAAAAAAAAAATACACCAGTACCACTATAATCACATTGCTCAAAACCAGTGATAAATCTAGAAAACAGCCAGAGGAGGAGAAAAAAGACATATTATCTACAAAGGAACACAATGCAAGCAAGGAGACAGTTGTGCCACATCTTTAAAAAAATAAAAGGTGTATATATATGTGTGTATATATGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATAAACAAAGAGTTTCTAACAATGGT
+
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
@25c99a91-29e7-413b-9a86-2f7b44bd088f
TATATAGCGAGTATATTGTGCCTCAAAATTTGGAAAATTTAGAAAAGTAGAAGAGAGCACATGTTATAGAAAAAAGCACTTATGATCCTCTTCTGCGTAGATGGTGTGTTTAAGGGGCCTTCATTTGCATTTCTTTCTAAACCTAACCTCTCTGATTTCCCTCTCTTCTTTACTTTCTCTTGTGTGTTGTACTGTTAGGGTGATGAGAAACAGCACATTCTCTATCCCTCAAACATGGTAGGGTATCCTCACTCAGCCTTATAAAGGATATGTTATCAGGTATGTCCTGCAGGCAGCCCTGATAACATCCTTTATAAAGGCTGAGTGACCCCTACCATGTTTGAGGGATGAGAATGTGCTGTTTCTCATCACCTAAGCATACAACACACAAATAAAAGTAAAGAAAAGAAAGGTAACTCAAAAGAAATGCAAATGAAGGCCCCTTAAACACCGTCTACACAGAGGATCATAAGTGCTTTTTTATAAACACACACTATCTTCTACTTTTCTAAATTTCCAATTTTCTAGGCACAATATCTCATATAGCAAATGT
+
@?@B?11.+++-/5+2*)*-,..+**+6:=;:;:@=8...**++,===666;;?B?;9)&&'(10&430/03GLCDFSG=<<=BSIEFGHFIEHGB>>>?DEEBB><:>A;6?A@BEBACEJSSECCDHFSABC@<8=(((@>><<EDD??---153003::>A?BG>@C8--*)2))&&&&'--767433345::.22;C766301..51333?ABDCBD@>>=;<87?;<=;<=;33'(*/,&&%)2'&&&&(+++))&*>=BADBBDFFMSDSIFJGGEDESFEGFC>>522=<<<;200)))+-+*-11-8;;>==;;*))*((''*++--33464640115784(''1216;7633>876988;/--*)0-*+-.'(+-14:652,*+-.5520))('%&'&''(*)*(&%$$#$((,.0111./--.-11240014345-34/-+(%%%'(*...**-.421.//1-,(())68<8.**--.13++**++,+,2072102899<;:95=<1.-.+.2732249:;;762,*%&&')*-)''&&&$##