Struct NMDAReceptor 

pub struct NMDAReceptor {
    pub open_probability: f64,
    pub tau_rise: f64,
    pub tau_decay: f64,
    pub alpha: f64,
    pub beta: f64,
    pub e_rev: f64,
    pub g_max: f64,
    pub mg_concentration: f64,
    /* private fields */
}

NMDA receptor - slow excitatory glutamate receptor with voltage dependence.

NMDA receptors have slower kinetics and are blocked by Mg2+ at resting potentials. They are critical for synaptic plasticity and learning.

Key features:

• Voltage-dependent Mg2+ block
• Slow kinetics (rise ~2 ms, decay ~100 ms)
• High Ca2+ permeability

Fields

open_probability: f64

Open probability (0 to 1).

tau_rise: f64

Rise time constant (ms).

tau_decay: f64

Decay time constant (ms).

alpha: f64

Forward binding rate (1/(mM·ms)).

beta: f64

Unbinding rate (1/ms).

e_rev: f64

Reversal potential (mV).

g_max: f64

Maximum conductance (nS).

mg_concentration: f64

Mg2+ concentration (mM).

Implementations

impl NMDAReceptor

pub fn new() -> Self

Create a new NMDA receptor with default parameters.

pub fn with_params(tau_rise: f64, tau_decay: f64, g_max: f64) -> Result<Self>

Create NMDA receptor with custom parameters.

pub fn mg_block(&self, voltage: f64) -> f64

Calculate voltage-dependent Mg2+ block.

Year and Stevens (1990) model: B(V) = 1 / (1 + [Mg2+]/3.57 * exp(-0.062 * V))

pub fn current(&self, voltage: f64) -> f64

Get the synaptic current (pA).

Trait Implementations

impl Clone for NMDAReceptor

fn clone(&self) -> NMDAReceptor

Returns a duplicate of the value.

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source.

impl Debug for NMDAReceptor

fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter.

impl Default for NMDAReceptor

fn default() -> Self

Returns the “default value” for a type.

impl ReceptorDynamics for NMDAReceptor

fn update( &mut self, nt_concentration: f64, _voltage: f64, dt: f64, ) -> Result<()>

Update receptor state given neurotransmitter concentration and membrane voltage.

fn get_conductance(&self) -> f64

Get the current open probability or conductance state.

fn reversal_potential(&self) -> f64

Get the reversal potential for this receptor (mV).

fn reset(&mut self)

Reset receptor to resting state.