Struct CalciumDynamics 

pub struct CalciumDynamics {
    pub concentration: f64,
    pub buffered: f64,
    pub resting_concentration: f64,
    pub tau_removal: f64,
    pub spike_influx: f64,
    pub buffer_capacity: f64,
    pub buffer_kon: f64,
    pub buffer_koff: f64,
    pub buffer_total: f64,
    pub volume: f64,
}

Calcium dynamics in a cellular compartment.

Models calcium concentration changes due to:

• Influx (voltage-gated channels, NMDA receptors)
• Buffering (calmodulin, calbindin, etc.)
• Extrusion (PMCA, NCX)
• Diffusion
• ER uptake and release

Fields

concentration: f64

Free calcium concentration (μM).

buffered: f64

Buffered calcium concentration (μM).

resting_concentration: f64

Resting calcium concentration (μM).

tau_removal: f64

Time constant for calcium removal (ms).

spike_influx: f64

Calcium influx per spike (μM).

buffer_capacity: f64

Buffer capacity (ratio of buffered to free calcium).

buffer_kon: f64

Buffer binding rate (1/(μM·ms)).

buffer_koff: f64

Buffer unbinding rate (1/ms).

buffer_total: f64

Total buffer concentration (μM).

volume: f64

Compartment volume (μm³).

Implementations

impl CalciumDynamics

pub fn new() -> Self

Create new calcium dynamics with default parameters.

pub fn presynaptic() -> Self

Create calcium dynamics for presynaptic terminal.

Presynaptic terminals have rapid calcium dynamics with high buffering.

pub fn postsynaptic() -> Self

Create calcium dynamics for postsynaptic spine.

Spines have intermediate calcium dynamics.

pub fn update(&mut self, influx: f64, dt: f64) -> Result<()>

Update calcium concentration over time.

Implements first-order removal and buffering dynamics.

Arguments

• influx - Calcium influx rate (μM/ms)
• dt - Time step (ms)

pub fn spike(&mut self)

Add calcium influx from spike.

pub fn add_influx(&mut self, amount: f64) -> Result<()>

Add calcium influx (e.g., from NMDA receptors).

Arguments

• amount - Amount of calcium to add (μM)

pub fn get_concentration(&self) -> f64

Get current free calcium concentration.

pub fn reset(&mut self)

Reset to resting state.

Trait Implementations

impl Clone for CalciumDynamics

fn clone(&self) -> CalciumDynamics

Returns a duplicate of the value.

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source.

impl Debug for CalciumDynamics

fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter.

impl Default for CalciumDynamics

fn default() -> Self

Returns the “default value” for a type.