AMPAReceptor

Struct AMPAReceptor 

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pub struct AMPAReceptor {
    pub open_probability: f64,
    pub tau_rise: f64,
    pub tau_decay: f64,
    pub alpha: f64,
    pub beta: f64,
    pub e_rev: f64,
    pub g_max: f64,
    /* private fields */
}
Expand description

AMPA receptor - fast excitatory glutamate receptor.

AMPA receptors mediate the majority of fast excitatory synaptic transmission. They have rapid kinetics with rise time ~0.2 ms and decay time ~2 ms.

Model: Two-state kinetic scheme C <-> O (Closed <-> Open) dr/dt = αNT - βr (rise) do/dt = r/τ_rise - o/τ_decay (opening and decay)

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§open_probability: f64

Open probability (0 to 1).

§tau_rise: f64

Rise time constant (ms).

§tau_decay: f64

Decay time constant (ms).

§alpha: f64

Forward binding rate (1/(mM·ms)).

§beta: f64

Unbinding rate (1/ms).

§e_rev: f64

Reversal potential (mV).

§g_max: f64

Maximum conductance (nS).

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impl AMPAReceptor

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pub fn new() -> Self

Create a new AMPA receptor with default parameters.

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pub fn with_params(tau_rise: f64, tau_decay: f64, g_max: f64) -> Result<Self>

Create AMPA receptor with custom parameters.

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pub fn current(&self, voltage: f64) -> f64

Get the synaptic current (pA).

Trait Implementations§

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impl Clone for AMPAReceptor

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fn clone(&self) -> AMPAReceptor

Returns a duplicate of the value. Read more
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fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source. Read more
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impl Debug for AMPAReceptor

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fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter. Read more
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impl Default for AMPAReceptor

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fn default() -> Self

Returns the “default value” for a type. Read more
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impl ReceptorDynamics for AMPAReceptor

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fn update( &mut self, nt_concentration: f64, _voltage: f64, dt: f64, ) -> Result<()>

Update receptor state given neurotransmitter concentration and membrane voltage. Read more
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fn get_conductance(&self) -> f64

Get the current open probability or conductance state.
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fn reversal_potential(&self) -> f64

Get the reversal potential for this receptor (mV).
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fn reset(&mut self)

Reset receptor to resting state.

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impl<T> Any for T
where T: 'static + ?Sized,

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fn type_id(&self) -> TypeId

Gets the TypeId of self. Read more
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impl<T> Borrow<T> for T
where T: ?Sized,

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fn borrow(&self) -> &T

Immutably borrows from an owned value. Read more
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impl<T> BorrowMut<T> for T
where T: ?Sized,

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fn borrow_mut(&mut self) -> &mut T

Mutably borrows from an owned value. Read more
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impl<T> CloneToUninit for T
where T: Clone,

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unsafe fn clone_to_uninit(&self, dest: *mut u8)

🔬This is a nightly-only experimental API. (clone_to_uninit)
Performs copy-assignment from self to dest. Read more
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impl<T> From<T> for T

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fn from(t: T) -> T

Returns the argument unchanged.

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impl<T, U> Into<U> for T
where U: From<T>,

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fn into(self) -> U

Calls U::from(self).

That is, this conversion is whatever the implementation of From<T> for U chooses to do.

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impl<T> ToOwned for T
where T: Clone,

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type Owned = T

The resulting type after obtaining ownership.
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fn to_owned(&self) -> T

Creates owned data from borrowed data, usually by cloning. Read more
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fn clone_into(&self, target: &mut T)

Uses borrowed data to replace owned data, usually by cloning. Read more
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impl<T, U> TryFrom<U> for T
where U: Into<T>,

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type Error = Infallible

The type returned in the event of a conversion error.
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fn try_from(value: U) -> Result<T, <T as TryFrom<U>>::Error>

Performs the conversion.
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impl<T, U> TryInto<U> for T
where U: TryFrom<T>,

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type Error = <U as TryFrom<T>>::Error

The type returned in the event of a conversion error.
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fn try_into(self) -> Result<U, <U as TryFrom<T>>::Error>

Performs the conversion.