Expand description
Re-exports§
pub use bias::build_expected_pos;pub use bias::corrected_effective_length_full;pub use bias::positional_factor;pub use bias::BiasInputs;pub use fld::ambig_frag_log_prob;pub use fld::smoothed_effective_length;pub use fld::DiscreteFld;pub use fld::FragmentLengthDistribution;pub use gcbias::build_expected_gc;pub use gcbias::gc_corrected_effective_length;pub use gcbias::gc_desc;pub use gcbias::gc_prefix;pub use gcbias::gc_ratio;pub use gcbias::GcFragModel;pub use gcbias::GcRank;pub use gcbias::GcStore;pub use gcbias::GcView;pub use gcbias::GC_SAMP_STRIDE;pub use libdetect::infer_format_from_counts;pub use libdetect::LibraryTypeDetector;pub use posbias::compute_length_quantiles;pub use posbias::length_class_index;pub use posbias::SimplePosBias;pub use posbias::NUM_LENGTH_CLASSES;pub use posbias::NUM_POS_BINS;pub use seqbias::build_expected;pub use seqbias::corrected_effective_length;pub use seqbias::LogBiasTable;pub use seqbias::SBModel;
Modules§
- bias
- Unified bias-corrected effective length: composes sequence-specific, GC, and
positional bias exactly as salmon’s
updateEffectiveLengthsdoes — a single conditional-FLD convolution whose per-fragment factor is the product of the enabled bias terms. - dumps
- Aux-output dump helpers shared by reads-mode and alignment-mode quant.
- fld
- Fragment-length distribution.
- gcbias
- Fragment-GC bias model (
GCFragModel). - libdetect
- Automatic library-type detection.
- posbias
- Positional fragment bias (
SimplePosBias) — a port of salmon’ssrc/model/SimplePosBias.cpp. - seqbias
- Sequence-specific bias model (
SBModel). - spline
- Cubic spline interpolation — a faithful port of the vendored
tk::spline(Tino Kluge) used by salmon’sSimplePosBias.
Constants§
- BIAS_
WEIGHT_ SCALE - Fixed-point scale for deterministic bias-model mass accumulation. Bias
observed models sum per-fragment posterior masses (each in
[0,1]) into bins; an f64+=is non-associative, so the accumulated model — and hence bias correction — varies with the worker-thread fragment partition (thread count). Accumulatinground_down(mass * BIAS_WEIGHT_SCALE)as integers makes the sum associative (order/thread-count independent).2^20keeps the per-contribution resolution at ~1e-6 (ample for these coarse models) while a bin total (~num_fragments × 2^20) stays far belowu64::MAX.
Functions§
- bias_
mass_ to_ fp - Quantize a bias mass (
[0,∞), typically a[0,1]posterior) to the fixed-point integer accumulator. Truncates (rounds toward zero) — cheaper thanround()and the ≤1-ULP downward bias is negligible and cancels under the model’s normalization.