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pmcore-0.22.1
PMcore
Rust library with the building blocks to create and implement new non-parametric algorithms for population pharmacokinetic modelling and their integration with Pmetrics.
Implemented functionality
- Solver for ODE-based population pharmacokinetic models
- Supports the Pmetrics data format for seamless integration
- Covariate support, carry-forward or linear interpolation
- Option to cache results for improved speed
- Powerful simulation engine
- Bestdose module for dose optimization
Available algorithms
This project aims to implement several algorithms for non-parametric population pharmacokinetic modelling.
- Non Parametric Adaptive Grid (NPAG)
- Non Parametric Optimal Design (NPOD)
- Non Parametric Simulated Annealing (NPSA)
In the future we also aim to support parametric algorithms, such as the Iterative 2-Stage Bayesian (IT2B)
Examples
Look at the examples in the examples folder to see how to use this library. The examples cover a variety of scenarios.
You may run them with the following command, e.g.
cargo run --example bimodal_ke --release
Documentation
For more information on how to use this crate, please review the documentation