Expand description
Output writers for simulated reads and ground truth files.
Provides FASTQ output (always) and optional golden BAM output for benchmarking alignment pipelines. Supports single-threaded and multi-threaded BGZF compression via pooled-writer.
Modulesยง
- cpg_
truth - Coverage-weighted per-CpG truth tally written as a MethylDackel-format bedGraph from simulated reads. Per-CpG ground-truth methylation tally and bedGraph writer.
- fastq
- FASTQ output for simulated reads.
- golden_
bam - Golden BAM output for ground-truth alignments.
- methylation_
bedgraph - Closed-form per-CpG population-fraction bedGraph writer derived from a
per-haplotype methylation bitmap; no simulated reads required.
Population-fraction methylation bedGraph in MethylDackel
extractformat.