Struct DiffSpliceParams 

pub struct DiffSpliceParams {
    pub prior_count: f64,
    pub robust: Option<bool>,
}

Tuning knobs for diff_splice and diff_splice_dge.

Fields

prior_count: f64

Prior count for the gene-level fit’s log-fold-change shrinkage. The exon-level fit is the caller’s and the reduced-model refit needs no shrunk coefficients.

robust: Option<bool>

Whether the gene-level empirical Bayes step Winsorises its moments. None follows edgeR: robust when the quasi-likelihood fit produced a per-gene df_prior. Ignored on the likelihood ratio path.

Implementations

impl DiffSpliceParams

pub fn new(prior_count: f64, robust: Option<bool>) -> Self

Builds a parameter set.

Params

• prior_count - Shrinkage prior for the gene-level fit, non-negative
• robust - Robust empirical Bayes, or None to let the fit decide

Returns

The parameter set. Validation happens in diff_splice.

Trait Implementations

impl Clone for DiffSpliceParams

fn clone(&self) -> Self

Returns a duplicate of the value.

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source.

impl Copy for DiffSpliceParams

impl Debug for DiffSpliceParams

fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter.

impl Default for DiffSpliceParams

fn default() -> Self

edgeR’s defaults: a prior count of 0.125 and an automatic robust.