pub struct QcConfig {Show 14 fields
pub n_mads: f32,
pub min_cell_nnz: usize,
pub min_counts_per_cell: f32,
pub mito_pattern: Option<String>,
pub mito_max_frac: Option<f32>,
pub ribo_pattern: Option<String>,
pub ribo_max_frac: Option<f32>,
pub mad_on_n_genes: bool,
pub mad_on_counts: bool,
pub mad_on_mito: bool,
pub feature_min_cells: usize,
pub drop_outliers: bool,
pub auto_cell_cutoff: bool,
pub qc_histogram: bool,
}Expand description
Configuration for cell QC. Plain struct (no clap) so non-clap crates
can construct it directly; the clap surface is QcArgs.
Fields§
§n_mads: f32MAD multiplier for the robust band (larger = more permissive).
min_cell_nnz: usizeNear-empty floor: cells with fewer than this many detected features (nnz across all rows) are masked at output, not dropped from training. 0 disables the floor.
min_counts_per_cell: f32Hard floor on total counts per cell, in addition to MAD. 0 disables.
mito_pattern: Option<String>Regex over row (feature) names selecting mitochondrial genes; enables
the per-cell mito-fraction metric. None disables it.
mito_max_frac: Option<f32>Optional hard max mitochondrial fraction (0..1).
ribo_pattern: Option<String>Regex selecting ribosomal genes (enables ribo-fraction metric).
ribo_max_frac: Option<f32>Optional hard max ribosomal fraction (0..1).
mad_on_n_genes: boolPer-cell metrics that drive MAD outlier flagging.
mad_on_counts: bool§mad_on_mito: bool§feature_min_cells: usizeFeature-axis QC (off by default): drop genes expressed in fewer than this many cells. 0 disables.
drop_outliers: boolMaster switch for the MAD train-drop tier. When false, only the
near-empty floor (output mask) is computed — used by inference
(predict/impute) so query cells are never silently dropped.
auto_cell_cutoff: boolAutomatic cell calling: pick the per-cell nnz cutoff at the trough
between the ambient and the cell peak (crate::qc::suggest_nnz_cutoff)
and train-drop every cell below it. So called-out ambient is removed
up front (via the caller’s mask_columns), not just output-masked — it
never shapes the model. The cutoff is authoritative; min_cell_nnz does
NOT floor it (it only drives the separate near-empty output mask). No-op
when there is no trough (unimodal) or when drop_outliers is false
(inference). Unlike the loader’s per-file empty-barcode gate, this runs
on the pooled cell axis.
qc_histogram: boolPrint the per-cell nnz histogram + the suggested/applied cutoff (the
same ASCII summary as data-beans squeeze --show-histogram).
Trait Implementations§
Auto Trait Implementations§
impl Forget for QcConfig
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impl RefUnwindSafe for QcConfig
impl Send for QcConfig
impl Sync for QcConfig
impl Unpin for QcConfig
impl UnsafeUnpin for QcConfig
impl UnwindSafe for QcConfig
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