Struct Synapse 

pub struct Synapse {
    pub synapse_type: SynapseType,
    pub weight: f64,
    pub w_max: f64,
    pub delay: f64,
    pub vesicle_pool: VesiclePool,
    pub neurotransmitter: Neurotransmitter,
    pub ampa: Option<AMPAReceptor>,
    pub nmda: Option<NMDAReceptor>,
    pub gabaa: Option<GABAAReceptor>,
    pub stdp: Option<STDP>,
    pub presynaptic_calcium: CalciumDynamics,
    pub postsynaptic_calcium: CalciumDynamics,
    /* private fields */
}

Complete synapse model.

Integrates all components of synaptic transmission:

• Presynaptic vesicle release
• Neurotransmitter diffusion and clearance
• Postsynaptic receptor activation
• Short-term plasticity (depression/facilitation)
• Long-term plasticity (STDP)
• Calcium dynamics

Fields

synapse_type: SynapseType

Synapse type.

weight: f64

Synaptic weight (0 to w_max).

w_max: f64

Maximum synaptic weight.

delay: f64

Synaptic delay (ms).

vesicle_pool: VesiclePool

Presynaptic vesicle pool.

neurotransmitter: Neurotransmitter

Neurotransmitter in synaptic cleft.

ampa: Option<AMPAReceptor>

AMPA receptor (for excitatory synapses).

nmda: Option<NMDAReceptor>

NMDA receptor (for excitatory synapses).

gabaa: Option<GABAAReceptor>

GABA-A receptor (for inhibitory synapses).

stdp: Option<STDP>

STDP plasticity rule.

presynaptic_calcium: CalciumDynamics

Presynaptic calcium dynamics.

postsynaptic_calcium: CalciumDynamics

Postsynaptic calcium dynamics.

Implementations

impl Synapse

pub fn excitatory(weight: f64, delay: f64) -> Result<Self>

Create a new excitatory (glutamatergic) synapse.

pub fn inhibitory(weight: f64, delay: f64) -> Result<Self>

Create a new inhibitory (GABAergic) synapse.

pub fn depressing_excitatory(weight: f64, delay: f64) -> Result<Self>

Create depressing excitatory synapse.

pub fn facilitating_excitatory(weight: f64, delay: f64) -> Result<Self>

Create facilitating excitatory synapse.

pub fn presynaptic_spike(&mut self, time: f64) -> Result<()>

Process presynaptic spike.

Arguments

• time - Current time (ms)

pub fn postsynaptic_spike(&mut self, time: f64) -> Result<()>

Process postsynaptic spike.

Arguments

• time - Current time (ms)

pub fn update( &mut self, time: f64, postsynaptic_voltage: f64, dt: f64, ) -> Result<()>

Update synapse dynamics.

Arguments

• time - Current time (ms)
• postsynaptic_voltage - Current postsynaptic membrane voltage (mV)
• dt - Time step (ms)

pub fn current(&self, voltage: f64) -> f64

Get total postsynaptic current.

Arguments

• voltage - Postsynaptic membrane voltage (mV)

Returns

Synaptic current (pA)

pub fn conductance(&self) -> f64

Get total postsynaptic conductance.

Returns

Synaptic conductance (nS)

pub fn effective_weight(&self) -> f64

Get effective synaptic strength (includes short-term plasticity).

pub fn set_weight(&mut self, weight: f64) -> Result<()>

Set synaptic weight.

pub fn enable_stdp( &mut self, a_plus: f64, a_minus: f64, tau_plus: f64, tau_minus: f64, ) -> Result<()>

Enable STDP plasticity.

pub fn disable_stdp(&mut self)

Disable STDP plasticity.

pub fn reset(&mut self)

Reset synapse to initial state.

Trait Implementations

impl Clone for Synapse

fn clone(&self) -> Synapse

Returns a duplicate of the value.

fn clone_from(&mut self, source: &Self)

Performs copy-assignment from source.

impl Debug for Synapse

fn fmt(&self, f: &mut Formatter<'_>) -> Result

Formats the value using the given formatter.