oricle 0.2.0

Pure-Rust bacterial oriC (replication origin) prediction via GC-skew (Z-curve) + DnaA-box clustering, Ori-Finder style, database-free
Documentation
# Real-genome oriC regression truth for oricle.
#
# Coordinates are DoriC (https://tubic.org/doric/) origins, re-derived on the
# CURRENT RefSeq accession version by exact-matching each DoriC oriC sequence
# against the genome (DoriC stores coordinates against older accession versions,
# so its stated numbers can be kilobases off). The E. coli entry additionally
# agrees with NCBI's own `rep_origin` annotation (3925744..3925975).
#
# Columns: accession  oric_start  oric_end  topology  tolerance_bp  note
# tolerance_bp is the max allowed distance from the predicted region to this
# interval for the regression to pass. Origins that wrap coordinate 1 have
# start > end.
#
# To run:  ORICLE_GENOME_DIR=/path/to/fastas cargo test --test regression -- --nocapture
# where the dir holds <accession>.fa (or .fasta/.fna) FASTA files. A dnaA gene
# hint TSV (<accession>.genes.tsv: seqname start end name) is used if present.
NC_000913.3	3925634	3926011	circular	5000	E. coli K-12 MG1655; NCBI rep_origin inside
NC_000964.3	4215390	409	circular	5000	B. subtilis 168; wraps origin
NC_002516.2	6264362	482	circular	5000	P. aeruginosa PAO1; wraps origin
NC_007795.1	1879	2155	circular	5000	S. aureus NCTC8325
NC_003210.1	2944342	317	circular	5000	L. monocytogenes EGD-e; wraps origin
NC_009089.1	1321	1561	circular	8000	C. difficile 630
NC_002505.1	2961047	234	circular	8000	V. cholerae chr1; wraps origin
NC_003888.3	4269844	4270777	linear	8000	S. coelicolor A3(2); linear, needs dnaA hint
NC_000962.3	1525	2051	circular	8000	M. tuberculosis H37Rv (biologically circular)