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Module input

Module input 

Source
Expand description

Read single-run biosaur2/KOTH feature TSVs or aligned KOTH intensity matrices.

Single-run tables retain feature-finding quality descriptors. Aligned matrices retain cross-run contributions and intensities, but omit several individual-feature descriptors. Optional matrix evidence columns supply validated summaries of KOTH’s LFQ extraction diagnostics. Raw-file feature finding is handled separately by uno::koth_ingest.

Columns are located BY NAME (order-independent). Required: massCalib, mz, charge, rtApex. Everything else is optional and read if present, with biosaur2 name aliases (nIsotopes↔n_isotopes, nScans↔n_scans).

Structs§

Feature
One LC-MS feature from a single run: a deisotoped, charge-resolved precursor mass at an apex RT, that we try to assign a peptide to.
FeatureMatrix
A single-run or aligned multi-run feature set.

Constants§

MATRIX_EVIDENCE_COLUMNS
Optional, label-independent summaries derived from KOTH’s LFQ details. All columns must precede n_contributing_runs; partial schemas are rejected. These describe extraction confidence, not peptide identification confidence.