dnase

Function dnase 

Source
pub fn dnase() -> Result<DataFrame, PolarsError>
Expand description

§Elisa assay of DNase

§Description:

The ‘DNase’ data frame has 176 rows and 3 columns of data obtained during development of an ELISA assay for the recombinant protein DNase in rat serum.

§Usage:

DNase

§Format:

  • An object of class ‘c(“nfnGroupedData”, “nfGroupedData”, “groupedData”, “data.frame”)’ containing the following columns:
  • Run an ordered factor with levels ‘10’ < … < ‘3’ indicating the assay run.
  • conc a numeric vector giving the known concentration of the protein.
  • density a numeric vector giving the measured optical density (dimensionless) in the assay. Duplicate optical density measurements were obtained.

§Details:

This dataset was originally part of package ‘nlme’, and that has methods (including for ‘[’, ‘as.data.frame’, ‘plot’ and ‘print’) for its grouped-data classes.

§Source:

Davidian, M. and Giltinan, D. M. (1995) Nonlinear Models for Repeated Measurement Data, Chapman & Hall (section 5.2.4, p. 134)

Pinheiro, J. C. and Bates, D. M. (2000) Mixed-effects Models in S and S-PLUS, Springer.

§Examples:

require(stats); require(graphics)

coplot(density ~ conc | Run, data = DNase,
show.given = FALSE, type = "b")
coplot(density ~ log(conc) | Run, data = DNase,
show.given = FALSE, type = "b")
## fit a representative run
fm1 <- nls(density ~ SSlogis( log(conc), Asym, xmid, scal ),
data = DNase, subset = Run == 1)
## compare with a four-parameter logistic
fm2 <- nls(density ~ SSfpl( log(conc), A, B, xmid, scal ),
data = DNase, subset = Run == 1)
summary(fm2)
anova(fm1, fm2)