pub fn indometh() -> Result<DataFrame, PolarsError>Expand description
§Pharmacokinetics of Indomethacin
§Description:
The ‘Indometh’ data frame has 66 rows and 3 columns of data on the pharmacokinetics of indometacin (or, older spelling, ‘indomethacin’).
§Usage:
Indometh
§Format:
An object of class ‘c(“nfnGroupedData”, “nfGroupedData”, “groupedData”, “data.frame”)’ containing the following columns:
- Subject an ordered factor with containing the subject codes. The ordering is according to increasing maximum response.
- time a numeric vector of times at which blood samples were drawn (hr).
- conc a numeric vector of plasma concentrations of indometacin (mcg/ml).
§Details:
Each of the six subjects were given an intravenous injection of indometacin.
This dataset was originally part of package ‘nlme’, and that has methods (including for ‘[’, ‘as.data.frame’, ‘plot’ and ‘print’) for its grouped-data classes.
§Source:
Kwan, Breault, Umbenhauer, McMahon and Duggan (1976) Kinetics of Indomethacin absorption, elimination, and enterohepatic circulation in man. Journal of Pharmacokinetics and Biopharmaceutics 4, 255-280.
Davidian, M. and Giltinan, D. M. (1995) Nonlinear Models for Repeated Measurement Data, Chapman & Hall (section 5.2.4, p. 129)
Pinheiro, J. C. and Bates, D. M. (2000) Mixed-effects Models in S and S-PLUS, Springer.
§See Also:
‘SSbiexp’ for models fitted to this dataset.