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voom

limma::voom

Function voom 

Source 
pub fn voom(
    counts: &Array2<f64>,
    design: Option<&Array2<f64>>,
    lib_size: Option<&Array1<f64>>,
    span: f64,
    adaptive_span: bool,
) -> Result<VoomOutput>
Expand description

voom(counts, design, lib.size, span, adaptive.span) with normalize.method = "none".

  • counts — n_genes x n_samples non-negative counts (no NaN).
  • design — optional n_samples x p design; defaults to a grand-mean intercept.
  • lib_size — optional per-sample library sizes; defaults to column sums.
  • span — LOWESS span used when adaptive_span is false.
  • adaptive_span — when true, the span is chosen by choose_lowess_span (small.n = 50, min.span = 0.3, power = 1/3), matching voom’s default.