Function varlociraptor::filtration::fdr::control_fdr

pub fn control_fdr<R, W>(
    inbcf: R,
    outbcf: Option<W>,
    events: &[SimpleEvent],
    vartype: Option<&VariantType>,
    alpha: LogProb,
    local: bool,
    smart: bool
) -> Result<()>
where
    R: AsRef<Path>,
    W: AsRef<Path>,

Print thresholds to control FDR of given calls at multiple levels.

Arguments

• inbcf - path to BCF with varlociraptor calls (None for stdin)
• outbcf - path to BCF with filtered varlociraptor calls (None for stdout)
• null_calls - calls under the null model, e.g. obtained by swapping tumor and normal sample
• writer - writer for resulting thresholds
• events - the set of events to control (sum of the probabilities of the individual events at a site)
• vartype - the variant type to consider
• alpha - the FDR threshold to control for