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varlociraptor-8.4.6
Varlociraptor
Varlociraptor implements a novel, unified fully uncertainty-aware approach to genomic variant calling in arbitrary scenarios.
Key features
- Calls SNVs and indels in all length ranges (from small to structural) with a unified statistical model.
- The statistical model entails all possible sources of uncertainty.
- Resulting variant calls can be filtered by false discovery rate. No parameter tuning necessary.
- Unbiased, maximum a posteriori allele frequency estimates are provided with each call.
Calling modes
- Tumor-normal-calling, classifying variants as somatic in tumor, somatic in normal, germline, or absent.
- Generic, grammar based calling, allowing to classify arbitrary scenarios.
For details, see the homepage: https://varlociraptor.github.io